(Q37847817)

24 August 2017

1 reference

title

Oxidative stress and cell membranes in the pathogenesis of Alzheimer's disease (English)

1 reference

24 August 2017

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Paul H Axelsen

1

1 reference

PubMed ID

21357903

24 August 2017

Hiroaki Komatsu

series ordinal

2

1 reference

PubMed ID

21357903

24 August 2017

Ian V J Murray

series ordinal

3

1 reference

24 August 2017

1 February 2011

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24 August 2017

1 reference

24 August 2017

26

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24 August 2017

1

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24 August 2017

54-69

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Protection against amyloid beta-peptide (1–42)-induced loss of phospholipid asymmetry in synaptosomal membranes by tricyclodecan-9-xanthogenate (D609) and ferulic acid ethyl ester: Implications for Alzheimer's disease

24 August 2017

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

How is protein aggregation in amyloidogenic diseases modulated by biological membranes?

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

Amino-terminus truncated apolipoprotein E is the major species in amyloid deposits in Alzheimer's disease-affected brains: a possible role for apolipoprotein E in Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

Interaction of nascent ApoE2, ApoE3, and ApoE4 isoforms expressed in mammalian cells with amyloid peptide beta (1-40). Relevance to Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

Methionine regulates copper/hydrogen peroxide oxidation products of Abeta

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

Histochemical detection of 4-hydroxynonenal protein in Alzheimer amyloid.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

Architecture of the Alzheimer's A beta P ion channel pore

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

Abeta ion channels. Prospects for treating Alzheimer's disease with Abeta channel blockers

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

Giant multilevel cation channels formed by Alzheimer disease amyloid beta-protein [A beta P-(1-40)] in bilayer membranes

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

Zn2+ interaction with Alzheimer amyloid beta protein calcium channels

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

Alzheimer disease amyloid beta protein forms calcium channels in bilayer membranes: blockade by tromethamine and aluminum

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

Lipid peroxidation in neurodegeneration: new insights into Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

Measurement of products of docosahexaenoic acid peroxidation, neuroprostanes, and neurofurans

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

Amyloid-β: a chameleon walking in two worlds: a review of the trophic and toxic properties of amyloid-β

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

Copper mediates dityrosine cross-linking of Alzheimer's amyloid-beta

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

Apolipoprotein E is essential for amyloid deposition in the APP(V717F) transgenic mouse model of Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

Lack of apolipoprotein E dramatically reduces amyloid beta-peptide deposition.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

Tau-mediated neurodegeneration in Alzheimer's disease and related disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

Neurotoxic, redox-competent Alzheimer's beta-amyloid is released from lipid membrane by methionine oxidation

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

Abeta40, either soluble or aggregated, is a remarkably potent antioxidant in cell-free oxidative systems

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

Hydrogen peroxide mediates amyloid beta protein toxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

Does human betaA4 exert a protective function against oxidative stress in Alzheimer's disease?

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

Apolipoprotein A-I(Milano) and apolipoprotein A-I(Paris) exhibit an antioxidant activity distinct from that of wild-type apolipoprotein A-I.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

Oxidative metabolites accelerate Alzheimer's amyloidogenesis by a two-step mechanism, eliminating the requirement for nucleation

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

A molecular switch in amyloid assembly: Met35 and amyloid beta-protein oligomerization

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

Two types of Alzheimer's beta-amyloid (1-40) peptide membrane interactions: aggregation preventing transmembrane anchoring versus accelerated surface fibril formation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

Proteomic identification of proteins oxidized by Abeta(1-42) in synaptosomes: implications for Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

The biological significance of plasmalogens in defense against oxidative damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

ACAT1 gene ablation increases 24(S)-hydroxycholesterol content in the brain and ameliorates amyloid pathology in mice with AD.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

The metallobiology of Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

Amyloid beta-peptide (1-42)-induced oxidative stress and neurotoxicity: implications for neurodegeneration in Alzheimer's disease brain. A review

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

Proteomics: a new approach to investigate oxidative stress in Alzheimer's disease brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

Amyloid beta-peptide(1-42) contributes to the oxidative stress and neurodegeneration found in Alzheimer disease brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

The critical role of methionine 35 in Alzheimer's amyloid beta-peptide (1-42)-induced oxidative stress and neurotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

Proteomics in Alzheimer's disease: insights into potential mechanisms of neurodegeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

Alzheimer's amyloid beta-peptide (1-42): involvement of methionine residue 35 in the oxidative stress and neurotoxicity properties of this peptide

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

Evidence that amyloid beta-peptide-induced lipid peroxidation and its sequelae in Alzheimer's disease brain contribute to neuronal death

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

In vivo oxidative stress in brain of Alzheimer disease transgenic mice: Requirement for methionine 35 in amyloid beta-peptide of APP.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

beta-Amyloid peptide free radical fragments initiate synaptosomal lipoperoxidation in a sequence-specific fashion: implications to Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

Methionine residue 35 is critical for the oxidative stress and neurotoxic properties of Alzheimer's amyloid beta-peptide 1-42.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

Lipid peroxidation and protein oxidation in Alzheimer's disease brain: potential causes and consequences involving amyloid beta-peptide-associated free radical oxidative stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

Roles of amyloid beta-peptide-associated oxidative stress and brain protein modifications in the pathogenesis of Alzheimer's disease and mild cognitive impairment

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

Protein-bound acrolein: a novel marker of oxidative stress in Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

Neuroprotective action of omega-3 polyunsaturated fatty acids against neurodegenerative diseases: evidence from animal studies

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

Dietary n-3 polyunsaturated fatty acid depletion activates caspases and decreases NMDA receptors in the brain of a transgenic mouse model of Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

Docosahexaenoic acid protects from dendritic pathology in an Alzheimer's disease mouse model

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

Amyloid-beta-induced ion flux in artificial lipid bilayers and neuronal cells: resolving a controversy

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

Proteomic identification of oxidatively modified proteins in Alzheimer's disease brain. Part I: creatine kinase BB, glutamine synthase, and ubiquitin carboxy-terminal hydrolase L-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

Proteomic identification of oxidatively modified proteins in Alzheimer's disease brain. Part II: dihydropyrimidinase-related protein 2, alpha-enolase and heat shock cognate 71.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

Modulation of phospholipid asymmetry in synaptosomal membranes by the lipid peroxidation products, 4-hydroxynonenal and acrolein: implications for Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

Proteomic identification of nitrated proteins in Alzheimer's disease brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

Advanced lipid peroxidation end-products in Alexander's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

Protofibrils, pores, fibrils, and neurodegeneration: separating the responsible protein aggregates from the innocent bystanders

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

Interaction of amyloid beta-protein with anionic phospholipids: possible involvement of Lys28 and C-terminus aliphatic amino acids.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

Treatment with a copper-zinc chelator markedly and rapidly inhibits beta-amyloid accumulation in Alzheimer's disease transgenic mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

Aqueous dissolution of Alzheimer's disease Abeta amyloid deposits by biometal depletion.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

Lipid membrane templates the ordering and induces the fibrillogenesis of Alzheimer's disease amyloid-beta peptide

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

Ganglioside GM1-Mediated Amyloid-beta Fibrillogenesis and Membrane Disruption†

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

Acceleration of amyloid fibril formation by specific binding of Abeta-(1-40) peptide to ganglioside-containing membrane vesicles

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

The interaction between Alzheimer amyloid beta(1-40) peptide and ganglioside GM1-containing membranes

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

Enhanced toxicity and cellular binding of a modified amyloid beta peptide with a methionine to valine substitution

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

Synaptic activity regulates interstitial fluid amyloid-beta levels in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

Natural oligomers of the amyloid-beta protein specifically disrupt cognitive function

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

Gene dose of apolipoprotein E type 4 allele and the risk of Alzheimer's disease in late onset families

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

The involvement of lipid rafts in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

Evidence that the beta-amyloid plaques of Alzheimer's disease represent the redox-silencing and entombment of abeta by zinc

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

Alzheimer's disease amyloid-beta binds copper and zinc to generate an allosterically ordered membrane-penetrating structure containing superoxide dismutase-like subunits

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

Metal ions, pH, and cholesterol regulate the interactions of Alzheimer's disease amyloid-beta peptide with membrane lipid

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

Involvement of oxidative stress-induced abnormalities in ceramide and cholesterol metabolism in brain aging and Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

Interaction between Alzheimer's Abeta(25-35) peptide and phospholipid bilayers: the role of cholesterol.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

Actin carbonylation: from a simple marker of protein oxidation to relevant signs of severe functional impairment.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

Membrane fusogenic activity of the Alzheimer's peptide A beta(1-42) demonstrated by small-angle neutron scattering

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

Insertion of externally administered amyloid beta peptide 25-35 and perturbation of lipid bilayers.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

Half-lives of docosahexaenoic acid in rat brain phospholipids are prolonged by 15 weeks of nutritional deprivation of n-3 polyunsaturated fatty acids

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

Calcium signaling and amyloid toxicity in Alzheimer disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

A role for synaptic zinc in activity-dependent Abeta oligomer formation and accumulation at excitatory synapses.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

Effects of sphingomyelin, cholesterol and zinc ions on the binding, insertion and aggregation of the amyloid Abeta(1-40) peptide in solid-supported lipid bilayers.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

Small molecule blockers of the Alzheimer Abeta calcium channel potently protect neurons from Abeta cytotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

Copper and Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

Oxidative stress precedes fibrillar deposition of Alzheimer's disease amyloid beta-peptide (1-42) in a transgenic Caenorhabditis elegans model.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

Pleomorphic copper coordination by Alzheimer's disease amyloid-beta peptide

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

Theoretical models of the ion channel structure of amyloid beta-protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

Insertion of Alzheimer's A beta 40 peptide into lipid monolayers

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

Amyloidogenic processing of the Alzheimer beta-amyloid precursor protein depends on lipid rafts

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

Amyloid ion channels: a porous argument or a thin excuse?

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

Chemistry and biochemistry of 4-hydroxynonenal, malonaldehyde and related aldehydes

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

Apolipoprotein E is a kinetic but not a thermodynamic inhibitor of amyloid formation: implications for the pathogenesis and treatment of Alzheimer disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

Bioinorganic chemistry of copper and zinc ions coordinated to amyloid-beta peptide

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

Plasmalogens: workhorse lipids of membranes in normal and injured neurons and glia

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

Membrane phospholipid alterations in Alzheimer's disease: deficiency of ethanolamine plasmalogens

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

Fish consumption and the risk of Alzheimer disease: is it time to make dietary recommendations?

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

Increased susceptibility to plasma lipid peroxidation in Alzheimer disease patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

Binding of Zn(II), Cu(II), and Fe(II) ions to Alzheimer's A beta peptide studied by fluorescence

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

Metal effects on the membrane interactions of amyloid-beta peptides

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

Redox proteomics: identification of oxidatively modified proteins.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

Reactive sulfur species: an emerging concept in oxidative stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

Disease and anatomic specificity of ethanolamine plasmalogen deficiency in Alzheimer's disease brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

Peripheral ethanolamine plasmalogen deficiency: a logical causative factor in Alzheimer's disease and dementia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

The role of lipid-protein interactions in amyloid-type protein fibril formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

Atomic force microscopy reveals defects within mica supported lipid bilayers induced by the amyloidogenic human amylin peptide.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

Increased cholesterol in Abeta-positive nerve terminals from Alzheimer's disease cortex

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

Model studies of cholesterol and ascorbate oxidation by copper complexes: relevance to Alzheimer's disease beta-amyloid metallochemistry

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

Lipid alterations in the earliest clinically recognizable stage of Alzheimer's disease: implication of the role of lipids in the pathogenesis of Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

Plasmalogen deficiency in early Alzheimer's disease subjects and in animal models: molecular characterization using electrospray ionization mass spectrometry

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

Substantial sulfatide deficiency and ceramide elevation in very early Alzheimer's disease: potential role in disease pathogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

Amyloid deposition as the central event in the aetiology of Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

Alzheimer's disease: the amyloid cascade hypothesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

A seed for Alzheimer amyloid in the brain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

A model for beta-amyloid aggregation and neurotoxicity based on free radical generation by the peptide: relevance to Alzheimer disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

Inhibition of the electrostatic interaction between beta-amyloid peptide and membranes prevents beta-amyloid-induced toxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

Methionine 35 oxidation reduces fibril assembly of the amyloid abeta-(1-42) peptide of Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

AMPAR removal underlies Abeta-induced synaptic depression and dendritic spine loss

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

Cu(II) potentiation of alzheimer abeta neurotoxicity. Correlation with cell-free hydrogen peroxide production and metal reduction.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

Amyloid-beta peptide (Abeta) neurotoxicity is modulated by the rate of peptide aggregation: Abeta dimers and trimers correlate with neurotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

The ACAT inhibitor CP-113,818 markedly reduces amyloid pathology in a mouse model of Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

Dietary n-6 PUFA deprivation for 15 weeks reduces arachidonic acid concentrations while increasing n-3 PUFA concentrations in organs of post-weaning male rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

Liquid chromatography/tandem mass spectrometry characterization of oxidized amyloid beta peptides as potential biomarkers of Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

Acceleration of amyloid beta-peptide aggregation by physiological concentrations of calcium

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

The efficacy of omega-3 fatty acids on cognitive function in aging and dementia: a systematic review

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

Truncated beta-amyloid peptide channels provide an alternative mechanism for Alzheimer's Disease and Down syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

The carboxy terminus of the beta amyloid protein is critical for the seeding of amyloid formation: implications for the pathogenesis of Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

Lipid peroxidation and free radical scavengers in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

Cholesterol is an important factor affecting the membrane insertion of beta-amyloid peptide (A beta 1-40), which may potentially inhibit the fibril formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

21 January 2018

Amyloid peptide channels

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

Cholesterol-dependent formation of GM1 ganglioside-bound amyloid beta-protein, an endogenous seed for Alzheimer amyloid

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

Interactions of amyloid beta-protein with various gangliosides in raft-like membranes: importance of GM1 ganglioside-bound form as an endogenous seed for Alzheimer amyloid

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

Formation of a membrane-active form of amyloid beta-protein in raft-like model membranes

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

Interaction between amyloid beta-protein aggregates and membranes

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

Lipids as modulators of proteolytic activity of BACE: involvement of cholesterol, glycosphingolipids, and anionic phospholipids in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

Cu(II) binding to monomeric, oligomeric, and fibrillar forms of the Alzheimer's disease amyloid-beta peptide.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

Permeabilization of lipid bilayers is a common conformation-dependent activity of soluble amyloid oligomers in protein misfolding diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

beta-Amyloid-induced dynamin 1 degradation is mediated by N-methyl-D-aspartate receptors in hippocampal neurons.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

Susceptibility of plasmenyl glycerophosphoethanolamine lipids containing arachidonate to oxidative degradation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

Novel metabolism of docosahexaenoic acid in neural cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

Chronic copper exposure exacerbates both amyloid and tau pathology and selectively dysregulates cdk5 in a mouse model of AD

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

A mechanistic link between oxidative stress and membrane mediated amyloidogenesis revealed by infrared spectroscopy

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

Amyloid-beta: an antioxidant that becomes a pro-oxidant and critically contributes to Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

Amyloid-beta is an antioxidant for lipoproteins in cerebrospinal fluid and plasma

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

Resistance of human cerebrospinal fluid to in vitro oxidation is directly related to its amyloid-beta content

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

Accelerated accumulation of amyloid beta proteins on oxidatively damaged lipid membranes

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

Early synergy between Abeta42 and oxidatively damaged membranes in promoting amyloid fibril formation by Abeta40.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

Kinetics of adsorption of beta-amyloid peptide Abeta(1-40) to lipid bilayers.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

Correlation of beta-amyloid aggregate size and hydrophobicity with decreased bilayer fluidity of model membranes

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

Profile of changes in lipid bilayer structure caused by beta-amyloid peptide

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

Evidence that plasmalogen is protective against oxidative stress in the rat brain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

Calcium dyshomeostasis and intracellular signalling in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

Amyloid beta ion channel: 3D structure and relevance to amyloid channel paradigm

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

Neurodegenerative disease: amyloid pores from pathogenic mutations.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

Are amyloid diseases caused by protein aggregates that mimic bacterial pore-forming toxins?

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

Amyloid-beta peptide disruption of lipid membranes and the effect of metal ions.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

The glial glutamate transporter, GLT-1, is oxidatively modified by 4-hydroxy-2-nonenal in the Alzheimer's disease brain: the role of Abeta1-42.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

Apolipoprotein E modulates Alzheimer's Abeta(1-42)-induced oxidative damage to synaptosomes in an allele-specific manner

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

Isoprostanes: formation, analysis and use as indices of lipid peroxidation in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

A detergent-insoluble membrane compartment contains A beta in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

Activation of phospholipase A2 by amyloid beta-peptides in vitro.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

Amyloid plaques in PSAPP mice bind less metal than plaques in human Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

A specific amyloid-beta protein assembly in the brain impairs memory

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

A diet enriched with the omega-3 fatty acid docosahexaenoic acid reduces amyloid burden in an aged Alzheimer mouse model.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

Amyloid beta protein forms ion channels: implications for Alzheimer's disease pathophysiology

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

Promotion of amyloid beta protein misfolding and fibrillogenesis by a lipid oxidation product

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

Ca2+-permeable AMPA receptors in synaptic plasticity and neuronal death

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

Amyloid beta interacts with the amyloid precursor protein: a potential toxic mechanism in Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

Elevated 4-hydroxynonenal in ventricular fluid in Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

Copper, iron and zinc in Alzheimer's disease senile plaques.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

Acrolein is increased in Alzheimer's disease brain and is toxic to primary hippocampal cultures

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

A role for docosahexaenoic acid-derived neuroprotectin D1 in neural cell survival and Alzheimer disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

Ethanolamine plasmalogens protect cholesterol-rich liposomal membranes from oxidation caused by free radicals

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

Ethanolamine plasmalogens prevent the oxidation of cholesterol by reducing the oxidizability of cholesterol in phospholipid bilayers

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

Apolipoprotein E: far more than a lipid transport protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

ApoE and Abeta1-42 interactions: effects of isoform and conformation on structure and function

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

An alternative interpretation of the amyloid Abeta hypothesis with regard to the pathogenesis of Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

Increased peroxidation and reduced antioxidant enzyme activity in Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

Oxidative stress hypothesis in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

Four-hydroxynonenal, a product of lipid peroxidation, is increased in the brain in Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

Physicochemical interactions of amyloid beta-peptide with lipid bilayers

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

Inhibitors of amyloid β-protein aggregation mediated by GM1-containing raft-like membranes

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

Evidence for excitoprotective and intraneuronal calcium-regulating roles for secreted forms of the beta-amyloid precursor protein.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

Increased oxidative stress in Alzheimer's disease as assessed with 4-hydroxynonenal but not malondialdehyde

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

Increased susceptibility of Alzheimer's disease temporal cortex to oxygen free radical-mediated processes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

Membrane disruption by Alzheimer beta-amyloid peptides mediated through specific binding to either phospholipids or gangliosides. Implications for neurotoxicity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

Characterization of the interactions of Alzheimer beta-amyloid peptides with phospholipid membranes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

Structural transitions associated with the interaction of Alzheimer beta-amyloid peptides with gangliosides.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

Implications of macromolecular crowding for protein assembly.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

Apolipoprotein E allele-specific antioxidant activity and effects on cytotoxicity by oxidative insults and beta-amyloid peptides

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

Structural membrane alterations in Alzheimer brains found to be associated with regional disease development; increased density of gangliosides GM1 and GM2 and loss of cholesterol in detergent-resistant membrane domains

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

The relationship between the aggregational state of the amyloid-beta peptides and free radical generation by the peptides

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

Lipid peroxidation in aging brain and Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

Peripheral F2-isoprostanes and F4-neuroprostanes are not increased in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

Plasmalogens protect unsaturated lipids against UV-induced oxidation in monolayer

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

Consumption of fish and n-3 fatty acids and risk of incident Alzheimer disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

Fish consumption and cognitive decline with age in a large community study

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

Non-cyclooxygenase-derived prostanoids (F2-isoprostanes) are formed in situ on phospholipids

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

Decreased lysophosphatidylcholine/phosphatidylcholine ratio in cerebrospinal fluid in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

The effect of macromolecular crowding on protein aggregation and amyloid fibril formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

Phospholipid mass is increased in fibroblasts bearing the Swedish amyloid precursor mutation

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

Free-radical-induced oxidation of arachidonoyl plasmalogen phospholipids: antioxidant mechanism and precursor pathway for bioactive eicosanoids

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

Membrane-mediated amyloidogenesis and the promotion of oxidative lipid damage by amyloid beta proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

Promotion of oxidative lipid membrane damage by amyloid beta proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

Apolipoprotein E immunoreactivity in cerebral amyloid deposits and neurofibrillary tangles in Alzheimer's disease and kuru plaque amyloid in Creutzfeldt-Jakob disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

Oxidation of cholesterol by amyloid precursor protein and beta-amyloid peptide.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

Thermodynamics of A beta(1-40) amyloid fibril elongation

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

Formation of toxic Abeta(1-40) fibrils on GM1 ganglioside-containing membranes mimicking lipid rafts: polymorphisms in Abeta(1-40) fibrils

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

Metalloenzyme-like activity of Alzheimer's disease beta-amyloid. Cu-dependent catalytic conversion of dopamine, cholesterol, and biological reducing agents to neurotoxic H(2)O(2).

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

Ether lipids in biomembranes

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

Proteins in human brain cortex are modified by oxidation, glycoxidation, and lipoxidation. Effects of Alzheimer disease and identification of lipoxidation targets.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

Isoprostanes: potential markers of oxidant stress in atherothrombotic disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

Detection of apolipoprotein E/dimeric soluble amyloid beta complexes in Alzheimer's disease brain supernatants.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

The amyloid beta-peptide is imported into mitochondria via the TOM import machinery and localized to mitochondrial cristae

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

Brain membrane phospholipid alterations in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

Fusogenic properties of the C-terminal domain of the Alzheimer beta-amyloid peptide.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

Unresolved issues in the link between docosahexaenoic acid and Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

Ion channel hypothesis for Alzheimer amyloid peptide neurotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

Regional membrane phospholipid alterations in Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

Oxidative injury in diseases of the central nervous system: focus on Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

Alzheimer disease beta-amyloid activity mimics cholesterol oxidase

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

Site-specific effects of peptide lipidation on beta-amyloid aggregation and cytotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

Amyloid ion channels: a common structural link for protein-misfolding disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

Efficient inhibition of the Alzheimer's disease beta-secretase by membrane targeting

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

Amyloid-beta(1-42) rapidly forms protofibrils and oligomers by distinct pathways in low concentrations of sodium dodecylsulfate

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

Amyloid beta, mitochondrial structural and functional dynamics in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

Hypercholesterolemia accelerates the Alzheimer's amyloid pathology in a transgenic mouse model

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

Delayed oxidative degradation of polyunsaturated diacyl phospholipids in the presence of plasmalogen phospholipids in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

The two-fold aspect of the interplay of amyloidogenic proteins with lipid membranes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

The biochemistry of the isoprostane, neuroprostane, and isofuran pathways of lipid peroxidation

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

Formation of isoprostane-like compounds (neuroprostanes) in vivo from docosahexaenoic acid.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

Isoprostanes. Novel markers of endogenous lipid peroxidation and potential mediators of oxidant injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

Apolipoproteins in human cerebrospinal fluid

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

Oxidative stress, antioxidants, and Alzheimer disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

Apolipoprotein E associates with beta amyloid peptide of Alzheimer's disease to form novel monofibrils. Isoform apoE4 associates more efficiently than apoE3

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

Copper(II) binding to amyloid-beta fibrils of Alzheimer's disease reveals a picomolar affinity: stoichiometry and coordination geometry are independent of Abeta oligomeric form

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

In Situ Oxidative Catalysis by Neurofibrillary Tangles and Senile Plaques in Alzheimer’s Disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

Plasma phosphatidylcholine docosahexaenoic acid content and risk of dementia and Alzheimer disease: the Framingham Heart Study.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

Simultaneous single-molecule fluorescence and conductivity studies reveal distinct classes of Abeta species on lipid bilayers

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

Increased lipoprotein oxidation in Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

Increased amyloid beta-peptide deposition in cerebral cortex as a consequence of apolipoprotein E genotype in late-onset Alzheimer disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

Hippocampal neuron loss exceeds amyloid plaque load in a transgenic mouse model of Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

Structural analysis of lipoprotein E particles

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

The amyloid beta peptide (Abeta(1-40)) is thermodynamically soluble at physiological concentrations

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

Amyloid-beta protein dimers isolated directly from Alzheimer's brains impair synaptic plasticity and memory

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

Solution structures of micelle-bound amyloid beta-(1-40) and beta-(1-42) peptides of Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

The amyloid-beta peptide of Alzheimer's disease binds Cu(I) in a linear bis-his coordination environment: insight into a possible neuroprotective mechanism for the amyloid-beta peptide

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

Profiling proteins related to amyloid deposited brain of Tg2576 mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

4-Hydroxynonenal-modified amyloid-beta peptide inhibits the proteasome: possible importance in Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

The oxidative stress metabolite 4-hydroxynonenal promotes Alzheimer protofibril formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

Cholesterol depletion inhibits the generation of beta-amyloid in hippocampal neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

The link between cholesterol and Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

Concentration dependent Cu2+ induced aggregation and dityrosine formation of the Alzheimer's disease amyloid-beta peptide.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

Copper-mediated amyloid-beta toxicity is associated with an intermolecular histidine bridge.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

Amyloid-beta and tau serve antioxidant functions in the aging and Alzheimer brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

Amyloid-β Deposition in Alzheimer Transgenic Mice Is Associated with Oxidative Stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

Oxidative damage in Alzheimer's.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

Advanced Maillard reaction end products are associated with Alzheimer disease pathology

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

Soluble amyloid oligomers increase bilayer conductance by altering dielectric structure

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

Neurofurans, novel indices of oxidant stress derived from docosahexaenoic acid

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

The Alzheimer's disease-associated amyloid beta-protein is an antimicrobial peptide

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

Induction of Alzheimer-like beta-amyloid immunoreactivity in the brains of rabbits with dietary cholesterol.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

Axonopathy and transport deficits early in the pathogenesis of Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

Isoform-specific interactions of human apolipoprotein E to an intermediate conformation of human Alzheimer amyloid-beta peptide.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

Copper in disorders with neurological symptoms: Alzheimer's, Menkes, and Wilson diseases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

X-ray absorption and diffraction studies of the metal binding sites in amyloid beta-peptide

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

The structure of the amyloid-beta peptide high-affinity copper II binding site in Alzheimer disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

Binding of human apolipoprotein E to synthetic amyloid beta peptide: isoform-specific effects and implications for late-onset Alzheimer disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

Cholesterol is necessary both for the toxic effect of Abeta peptides on vascular smooth muscle cells and for Abeta binding to vascular smooth muscle cell membranes

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

Oxidatively modified GST and MRP1 in Alzheimer's disease brain: implications for accumulation of reactive lipid peroxidation products

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

Apolipoprotein E allele-dependent antioxidant activity in brains with Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

Alzheimer beta-amyloid peptide 25-35: electrostatic interactions with phospholipid membranes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

Self-association of beta-amyloid peptide (1-40) in solution and binding to lipid membranes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

Methylation of the imidazole side chains of the Alzheimer disease amyloid-beta peptide results in abolition of superoxide dismutase-like structures and inhibition of neurotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

Peroxynitrite-mediated modification of proteins at physiological carbon dioxide concentration: pH dependence of carbonyl formation, tyrosine nitration, and methionine oxidation

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

A mouse model of amyloid beta oligomers: their contribution to synaptic alteration, abnormal tau phosphorylation, glial activation, and neuronal loss in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

Ultrastructural evidence of fibrillar beta-amyloid associated with neuronal membranes in behaviorally characterized aged dog brains.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

Effects of secreted oligomers of amyloid beta-protein on hippocampal synaptic plasticity: a potent role for trimers.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

Cellular copper import by nanocarrier systems, intracellular availability, and effects on amyloid beta peptide secretion.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

The role of tau in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

Low serum cholesteryl ester-docosahexaenoic acid levels in Alzheimer's disease: a case-control study.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

Current status of acrolein as a lipid peroxidation product

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

4-Hydroxy-2-nonenal: a product and mediator of oxidative stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

Acrolein is a product of lipid peroxidation reaction. Formation of free acrolein and its conjugate with lysine residues in oxidized low density lipoproteins.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

Protein-bound acrolein: potential markers for oxidative stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

Modification of histidine residues in proteins by reaction with 4-hydroxynonenal

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

Site-specific modification of Alzheimer's peptides by cholesterol oxidation products enhances aggregation energetics and neurotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

Review: Alzheimer's amyloid beta-peptide-associated free radical oxidative stress and neurotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

Deletion of Abca1 increases Abeta deposition in the PDAPP transgenic mouse model of Alzheimer disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

Formation of amyloids by Abeta-(1-42) on NGF-differentiated PC12 cells: roles of gangliosides and cholesterol

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

GM1 ganglioside-mediated accumulation of amyloid beta-protein on cell membranes

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

Naturally secreted oligomers of amyloid beta protein potently inhibit hippocampal long-term potentiation in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

Amyloid beta-protein fibrillogenesis. Detection of a protofibrillar intermediate.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

Reduction in cholesterol and sialic acid content protects cells from the toxic effects of beta-amyloid peptides

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

Cellular membrane composition defines A beta-lipid interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

Lipid-induced beta-amyloid peptide assemblage fragmentation

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

Increased levels of 4-hydroxynonenal and acrolein, neurotoxic markers of lipid peroxidation, in the brain in Mild Cognitive Impairment and early Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

Amyloid-beta membrane binding and permeabilization are distinct processes influenced separately by membrane charge and fluidity

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

Transgenic C. elegans as a model in Alzheimer's research

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

Amyloid beta protein (Abeta) starts to deposit as plasma membrane-bound form in diffuse plaques of brains from hereditary cerebral hemorrhage with amyloidosis-Dutch type, Alzheimer disease and nondemented aged subjects

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

Accumulation and aggregation of amyloid beta-protein in late endosomes of Niemann-pick type C cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

GM1 ganglioside-bound amyloid beta-protein (A beta): a possible form of preamyloid in Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

Characterization of the binding of amyloid-beta peptide to cell culture-derived native apolipoprotein E2, E3, and E4 isoforms and to isoforms from human plasma

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

Reduced membrane lipids in the cortex of Alzheimer's disease transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

Abeta42-peptide assembly on lipid bilayers

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

Amyloid-beta peptide assembly: a critical step in fibrillogenesis and membrane disruption

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

Pore-forming proteins share structural and functional homology with amyloid oligomers

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

New insights on how metals disrupt amyloid beta-aggregation and their effects on amyloid-beta cytotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

Oxidation of cholesterol catalyzed by amyloid beta-peptide (Abeta)-Cu complex on lipid membrane

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

Prostaglandin H(2)-derived adducts of proteins correlate with Alzheimer's disease severity

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

Plasma concentrations of vitamins A and E and carotenoids in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

Apolipoprotein E and low density lipoprotein receptor-related protein facilitate intraneuronal Abeta42 accumulation in amyloid model mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

Metabolite-initiated protein misfolding may trigger Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

Regulation of gamma-secretase activity in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

Hippocampal membrane alteration in Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

β-Sheet Structured β-Amyloid(1-40) Perturbs Phosphatidylcholine Model Membranes

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

The Aβ Peptide of Alzheimer's Disease Directly Produces Hydrogen Peroxide through Metal Ion Reduction†

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

Amyloid-associated proteins α1-antichymotrypsin and apolipoprotein E promote assembly of Alzheimer β-protein into filaments

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00024.2010

10.1152/PHYSIOL.00024.2010

21 January 2018

Identifiers

DOI

1 reference

24 August 2017

1 reference

PubMed ID

21357903