(Q39026438)

8 September 2017

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title

Genome-Editing Technologies: Principles and Applications (English)

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8 September 2017

Thomas Gaj

1

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8 September 2017

Shannon J Sirk

series ordinal

2

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8 September 2017

Sai-Lan Shui

series ordinal

3

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8 September 2017

Jia Liu

series ordinal

4

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8 September 2017

publication date

1 December 2016

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Cold Spring Harbor Perspectives in Biology

8 September 2017

published in

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8 September 2017

volume

8

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8 September 2017

issue

12

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megaTALs: a rare-cleaving nuclease architecture for therapeutic genome engineering

8 September 2017

cites work

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12 December 2020

Non-transgenic Plant Genome Editing Using Purified Sequence-Specific Nucleases

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12 December 2020

TALE nickase-mediated SP110 knockin endows cattle with increased resistance to tuberculosis

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12 December 2020

Light-inducible spatiotemporal control of gene activation by customizable zinc finger transcription factors

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12 December 2020

Complete decoding of TAL effectors for DNA recognition

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12 December 2020

Multiplex metabolic pathway engineering using CRISPR/Cas9 in Saccharomyces cerevisiae.

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12 December 2020

Multiplexed and programmable regulation of gene networks with an integrated RNA and CRISPR/Cas toolkit in human cells.

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12 December 2020

DNA recognition by Cys2His2 zinc finger proteins

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12 December 2020

In vivo genome editing improves muscle function in a mouse model of Duchenne muscular dystrophy.

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12 December 2020

CRISPR-Cas9 Based Engineering of Actinomycetal Genomes

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12 December 2020

Large genomic fragment deletion and functional gene cassette knock-in via Cas9 protein mediated genome editing in one-cell rodent embryos

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12 December 2020

Genome-scale CRISPR-Cas9 knockout screening in human cells

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12 December 2020

The CRISPR/Cas9 System Facilitates Clearance of the Intrahepatic HBV Templates In Vivo

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12 December 2020

RNA-guided editing of bacterial genomes using CRISPR-Cas systems

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12 December 2020

Design of polydactyl zinc-finger proteins for unique addressing within complex genomes

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12 December 2020

Highly efficient endogenous human gene correction using designed zinc-finger nucleases

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12 December 2020

Gene editing of CCR5 in autologous CD4 T cells of persons infected with HIV

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12 December 2020

Double nicking by RNA-guided CRISPR Cas9 for enhanced genome editing specificity

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12 December 2020

Epigenetic reprogramming of cancer cells via targeted DNA methylation.

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12 December 2020

A CRISPR-Cas9 gene drive system targeting female reproduction in the malaria mosquito vector Anopheles gambiae

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12 December 2020

Designable DNA-binding domains enable construction of logic circuits in mammalian cells

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12 December 2020

Homology-directed repair in rodent zygotes using Cas9 and TALEN engineered proteins

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12 December 2020

High-throughput screening of a CRISPR/Cas9 library for functional genomics in human cells

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12 December 2020

Modulation of drug resistance by artificial transcription factors.

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12 December 2020

CAS9 transcriptional activators for target specificity screening and paired nickases for cooperative genome engineering

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12 December 2020

Genetic engineering of human pluripotent cells using TALE nucleases

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12 December 2020

Genome Engineering Using Adeno-associated Virus: Basic and Clinical Research Applications

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12 December 2020

Iterative capped assembly: rapid and scalable synthesis of repeat-module DNA such as TAL effectors from individual monomers

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12 December 2020

In vivo genome editing of the albumin locus as a platform for protein replacement therapy

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12 December 2020

Targeted genome engineering in human cells with the Cas9 RNA-guided endonuclease

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12 December 2020

Chromosomal deletions and inversions mediated by TALENs and CRISPR/Cas in zebrafish.

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12 December 2020

Targeted gene disruption in somatic zebrafish cells using engineered TALENs

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12 December 2020

Highly specific zinc finger proteins obtained by directed domain shuffling and cell-based selection

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12 December 2020

A split-Cas9 architecture for inducible genome editing and transcription modulation

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12 December 2020

FLASH assembly of TALENs for high-throughput genome editing

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12 December 2020

Targeted genome editing in human cells with zinc finger nucleases constructed via modular assembly

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12 December 2020

Efficient design and assembly of custom TALEN and other TAL effector-based constructs for DNA targeting

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12 December 2020

A simple cipher governs DNA recognition by TAL effectors

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12 December 2020

In vitro selection of zinc fingers with altered DNA-binding specificity

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12 December 2020

Rapid reverse genetic screening using CRISPR in zebrafish

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12 December 2020

RNA-programmed genome editing in human cells

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12 December 2020

Improved specificity of TALE-based genome editing using an expanded RVD repertoire

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12 December 2020

Protein delivery using Cys2-His2 zinc-finger domains

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12 December 2020

CasEMBLR: Cas9-Facilitated Multiloci Genomic Integration of in Vivo Assembled DNA Parts in Saccharomyces cerevisiae.

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12 December 2020

CRISPR-mediated Activation of Latent HIV-1 Expression

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12 December 2020

Transcription activator-like effector hybrids for conditional control and rewiring of chromosomal transgene expression

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12 December 2020

Chimeric TALE recombinases with programmable DNA sequence specificity

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12 December 2020

Fusion of catalytically inactive Cas9 to FokI nuclease improves the specificity of genome modification

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12 December 2020

DNA-binding-domain fusions enhance the targeting range and precision of Cas9.

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12 December 2020

RNA-guided transcriptional regulation in planta via synthetic dCas9-based transcription factors.

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12 December 2020

Inhibition of herpes simplex virus 1 gene expression by designer zinc-finger transcription factors

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12 December 2020

Locked and proteolysis-based transcription activator-like effector (TALE) regulation

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12 December 2020

In vivo genome editing using Staphylococcus aureus Cas9

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12 December 2020

Concerning RNA-guided gene drives for the alteration of wild populations

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12 December 2020

Targeted gene knockout in mammalian cells by using engineered zinc-finger nucleases.

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12 December 2020

Knockout rats generated by embryo microinjection of TALENs.

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12 December 2020

A general strategy for selecting high-affinity zinc finger proteins for diverse DNA target sites

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12 December 2020

Selection-free gene repair after adenoviral vector transduction of designer nucleases: rescue of dystrophin synthesis in DMD muscle cell populations.

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12 December 2020

GAL4-VP16 is an unusually potent transcriptional activator

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12 December 2020

Enabling functional genomics with genome engineering

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12 December 2020

Simultaneous generation and germline transmission of multiple gene mutations in rat using CRISPR-Cas systems.

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12 December 2020

mRNA transfection of a novel TAL effector nuclease (TALEN) facilitates efficient knockout of HIV co-receptor CCR5.

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12 December 2020

Optimized tuning of TALEN specificity using non-conventional RVDs.

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12 December 2020

Generation of a nicking enzyme that stimulates site-specific gene conversion from the I-AniI LAGLIDADG homing endonuclease

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12 December 2020

Human hematopoietic stem/progenitor cells modified by zinc-finger nucleases targeted to CCR5 control HIV-1 in vivo

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12 December 2020

Simultaneous editing of three homoeoalleles in hexaploid bread wheat confers heritable resistance to powdery mildew.

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12 December 2020

Therapeutic genome editing by combined viral and non-viral delivery of CRISPR system components in vivo

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12 December 2020

Improved soybean oil quality by targeted mutagenesis of the fatty acid desaturase 2 gene family

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12 December 2020

Efficient genome engineering in human pluripotent stem cells using Cas9 from Neisseria meningitidis

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12 December 2020

Genetic reprogramming of tumor cells by zinc finger transcription factors

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12 December 2020

Homing endonucleases from mobile group I introns: discovery to genome engineering

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12 December 2020

CRISPR/Cas9 systems targeting β-globin and CCR5 genes have substantial off-target activity

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12 December 2020

Positive and negative regulation of endogenous genes by designed transcription factors

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12 December 2020

Development of zinc finger domains for recognition of the 5'-CNN-3' family DNA sequences and their use in the construction of artificial transcription factors

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12 December 2020

An unbiased genome-wide analysis of zinc-finger nuclease specificity

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12 December 2020

A dual AAV system enables the Cas9-mediated correction of a metabolic liver disease in newborn mice

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12 December 2020

High Efficiency, Homology-Directed Genome Editing in Caenorhabditis elegans Using CRISPR-Cas9 Ribonucleoprotein Complexes.

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12 December 2020

Human zinc fingers as building blocks in the construction of artificial transcription factors.

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12 December 2020

A rapid, generally applicable method to engineer zinc fingers illustrated by targeting the HIV-1 promoter

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12 December 2020

Saturation editing of genomic regions by multiplex homology-directed repair

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12 December 2020

Potent and Targeted Activation of Latent HIV-1 Using the CRISPR/dCas9 Activator Complex

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12 December 2020

Targeting DNA double-strand breaks with TAL effector nucleases

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12 December 2020

The Crystal Structure of TAL Effector PthXo1 Bound to Its DNA Target

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12 December 2020

A TALE nuclease architecture for efficient genome editing

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12 December 2020

CRISPR-Cas9-based photoactivatable transcription system.

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12 December 2020

Tunable and multifunctional eukaryotic transcription factors based on CRISPR/Cas

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12 December 2020

A library of TAL effector nucleases spanning the human genome

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12 December 2020

Crystal Structure of Cas9 in Complex with Guide RNA and Target DNA

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12 December 2020

Engineered zinc finger nickases induce homology-directed repair with reduced mutagenic effects

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12 December 2020

Directed evolution of an enhanced and highly efficient FokI cleavage domain for zinc finger nucleases

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12 December 2020

Redesigning Recombinase Specificity for Safe Harbor Sites in the Human Genome

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12 December 2020

Safeguarding CRISPR-Cas9 gene drives in yeast

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12 December 2020

Generation of knock-in primary human T cells using Cas9 ribonucleoproteins.

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12 December 2020

Induced DNA demethylation by targeting Ten-Eleven Translocation 2 to the human ICAM-1 promoter

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12 December 2020

Cell-penetrating peptide-mediated delivery of TALEN proteins via bioconjugation for genome engineering

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12 December 2020

Genome editing with Cas9 in adult mice corrects a disease mutation and phenotype.

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12 December 2020

Conditionally Stabilized dCas9 Activator for Controlling Gene Expression in Human Cell Reprogramming and Differentiation

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12 December 2020

Meganucleases and other tools for targeted genome engineering: perspectives and challenges for gene therapy

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12 December 2020

Engineered CRISPR-Cas9 nucleases with altered PAM specificities

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12 December 2020

Toward a code for the interactions of zinc fingers with DNA: selection of randomized fingers displayed on phage

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12 December 2020

Homing endonucleases: from microbial genetic invaders to reagents for targeted DNA modification

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12 December 2020

Genome editing with engineered zinc finger nucleases

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12 December 2020

Therapeutic genome editing: prospects and challenges

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12 December 2020

Cas9 gRNA engineering for genome editing, activation and repression.

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12 December 2020

Targeted gene knockout by direct delivery of zinc-finger nuclease proteins

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12 December 2020

Engineering human tumour-associated chromosomal translocations with the RNA-guided CRISPR-Cas9 system

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12 December 2020

Establishment of HIV-1 resistance in CD4+ T cells by genome editing using zinc-finger nucleases

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12 December 2020

Selection-free zinc-finger-nuclease engineering by context-dependent assembly (CoDA)

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12 December 2020

Induction of homologous recombination in mammalian chromosomes by using the I-SceI system of Saccharomyces cerevisiae

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12 December 2020

Genetic screens in human cells using the CRISPR-Cas9 system

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12 December 2020

Broad specificity profiling of TALENs results in engineered nucleases with improved DNA-cleavage specificity

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12 December 2020

TALEN-based knockout library for human microRNAs

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12 December 2020

Gene targeting using zinc finger nucleases

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12 December 2020

Synthesizing AND gate genetic circuits based on CRISPR-Cas9 for identification of bladder cancer cells

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12 December 2020

An improved zinc-finger nuclease architecture for highly specific genome editing

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12 December 2020

E-CRISP: fast CRISPR target site identification.

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12 December 2020

RNA-guided genetic silencing systems in bacteria and archaea

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12 December 2020

Synergistic and tunable human gene activation by combinations of synthetic transcription factors

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12 December 2020

Toward controlling gene expression at will: selection and design of zinc finger domains recognizing each of the 5'-GNN-3' DNA target sequences

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12 December 2020

Continuous directed evolution of DNA-binding proteins to improve TALEN specificity.

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12 December 2020

A synthetic homing endonuclease-based gene drive system in the human malaria mosquito

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12 December 2020

Chimeric recombinases with designed DNA sequence recognition

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12 December 2020

Direct activation of human and mouse Oct4 genes using engineered TALE and Cas9 transcription factors.

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12 December 2020

Comprehensive interrogation of natural TALE DNA-binding modules and transcriptional repressor domains

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12 December 2020

Efficient modification of CCR5 in primary human hematopoietic cells using a megaTAL nuclease and AAV donor template

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12 December 2020

Heritable targeted gene disruption in zebrafish using designed zinc-finger nucleases

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12 December 2020

Expanding the zinc-finger recombinase repertoire: directed evolution and mutational analysis of serine recombinase specificity determinants.

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12 December 2020

Optical control of mammalian endogenous transcription and epigenetic states

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12 December 2020

Zinc finger-DNA recognition: crystal structure of a Zif268-DNA complex at 2.1 A

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12 December 2020

Targeted genome editing by lentiviral protein transduction of zinc-finger and TAL-effector nucleases

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12 December 2020

High-fidelity CRISPR-Cas9 nucleases with no detectable genome-wide off-target effects.

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12 December 2020

Dimeric CRISPR RNA-guided FokI nucleases for highly specific genome editing

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12 December 2020

Correction of a genetic disease in mouse via use of CRISPR-Cas9.

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12 December 2020

Stimulation of homologous recombination through targeted cleavage by chimeric nucleases

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12 December 2020

A CRISPR/Cas9-based system for reprogramming cell lineage specification.

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12 December 2020

Improving CRISPR-Cas nuclease specificity using truncated guide RNAs

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12 December 2020

Generation of a monkey with MECP2 mutations by TALEN-based gene targeting

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12 December 2020

Enhancing Gene Targeting with Designed Zinc Finger Nucleases

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12 December 2020

Chimeric nucleases stimulate gene targeting in human cells

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12 December 2020

Orthogonal gene knockout and activation with a catalytically active Cas9 nuclease

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12 December 2020

Small molecule-triggered Cas9 protein with improved genome-editing specificity

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12 December 2020

DNA-free genome editing in plants with preassembled CRISPR-Cas9 ribonucleoproteins

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12 December 2020

Robust, synergistic regulation of human gene expression using TALE activators

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12 December 2020

Highly active zinc-finger nucleases by extended modular assembly

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12 December 2020

Highly efficient RNA-guided genome editing in human cells via delivery of purified Cas9 ribonucleoproteins

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12 December 2020

Induction of angiogenesis in a mouse model using engineered transcription factors

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12 December 2020

Enabling plant synthetic biology through genome engineering

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12 December 2020

Development of zinc finger domains for recognition of the 5'-ANN-3' family of DNA sequences and their use in the construction of artificial transcription factors

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12 December 2020

Chemically regulated zinc finger transcription factors

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12 December 2020

Adenoviral vector DNA for accurate genome editing with engineered nucleases.

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12 December 2020

CRISPR/gRNA-directed synergistic activation mediator (SAM) induces specific, persistent and robust reactivation of the HIV-1 latent reservoirs

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12 December 2020

An optimized two-finger archive for ZFN-mediated gene targeting

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12 December 2020

CRISPR RNA-guided activation of endogenous human genes

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12 December 2020

Efficient genome editing in zebrafish using a CRISPR-Cas system

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12 December 2020

Reactivation of Latent HIV-1 Expression by Engineered TALE Transcription Factors.

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12 December 2020

Highly specific epigenome editing by CRISPR-Cas9 repressors for silencing of distal regulatory elements

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12 December 2020

Structural Basis for Sequence-Specific Recognition of DNA by TAL Effectors

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12 December 2020

Knockout rats via embryo microinjection of zinc-finger nucleases

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12 December 2020

CRISPR/Cas, the immune system of bacteria and archaea

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12 December 2020

Towards a new era in medicine: therapeutic genome editing

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12 December 2020

Genome-wide CRISPR screen in a mouse model of tumor growth and metastasis

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12 December 2020

Genome-editing Technologies for Gene and Cell Therapy

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12 December 2020

Gene drive systems for insect disease vectors

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12 December 2020

Genome editing in the human malaria parasite Plasmodium falciparum using the CRISPR-Cas9 system.

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12 December 2020

Engineering polydactyl zinc-finger transcription factors

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12 December 2020

Attenuation of HIV-1 replication in primary human cells with a designed zinc finger transcription factor.

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12 December 2020

Enhancing the specificity of recombinase-mediated genome engineering through dimer interface redesign.

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12 December 2020

Repression of the HIV-1 5' LTR promoter and inhibition of HIV-1 replication by using engineered zinc-finger transcription factors

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12 December 2020

Genome-wide recessive genetic screening in mammalian cells with a lentiviral CRISPR-guide RNA library

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12 December 2020

A comprehensive approach to zinc-finger recombinase customization enables genomic targeting in human cells

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12 December 2020

In vivo genome editing restores haemostasis in a mouse model of haemophilia

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12 December 2020

Structural basis of PAM-dependent target DNA recognition by the Cas9 endonuclease

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12 December 2020

Locus-specific editing of histone modifications at endogenous enhancers

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12 December 2020

Robust ZFN-mediated genome editing in adult hemophilic mice.

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12 December 2020

Postnatal genome editing partially restores dystrophin expression in a mouse model of muscular dystrophy.

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12 December 2020

Regulation of endogenous gene expression with a small-molecule dimerizer

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12 December 2020

Phenotypic alteration of eukaryotic cells using randomized libraries of artificial transcription factors

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12 December 2020

In vivo selection of combinatorial libraries and designed affinity maturation of polydactyl zinc finger transcription factors for ICAM-1 provides new insights into gene regulation

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12 December 2020

TAL effector RVD specificities and efficiencies

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12 December 2020

In vivo genome editing using nuclease-encoding mRNA corrects SP-B deficiency

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12 December 2020

Enhancing zinc-finger-nuclease activity with improved obligate heterodimeric architectures

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12 December 2020

TALENs facilitate targeted genome editing in human cells with high specificity and low cytotoxicity

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12 December 2020

Targeted gene addition to a predetermined site in the human genome using a ZFN-based nicking enzyme

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12 December 2020

Synthetic CRISPR RNA-Cas9-guided genome editing in human cells

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12 December 2020

Krüppel-associated boxes are potent transcriptional repression domains

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12 December 2020

A light-inducible CRISPR-Cas9 system for control of endogenous gene activation

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12 December 2020

Toward controlling gene expression at will: specific regulation of the erbB-2/HER-2 promoter by using polydactyl zinc finger proteins constructed from modular building blocks

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12 December 2020

Reprogramming to pluripotency using designer TALE transcription factors targeting enhancers

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12 December 2020

DNA targeting specificity of RNA-guided Cas9 nucleases

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12 December 2020

In Vivo Transcriptional Activation Using CRISPR/Cas9 in Drosophila

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12 December 2020

A CRISPR-Based Screen Identifies Genes Essential for West-Nile-Virus-Induced Cell Death

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12 December 2020

Orthogonal Cas9 proteins for RNA-guided gene regulation and editing

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12 December 2020

Inhibition of human immunodeficiency virus type 1 replication with artificial transcription factors targeting the highly conserved primer-binding site

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12 December 2020

Breaking the code of DNA binding specificity of TAL-type III effectors

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12 December 2020

A transcription activator-like effector (TALE) induction system mediated by proteolysis

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12 December 2020

Selection of chromosomal DNA libraries using a multiplex CRISPR system

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12 December 2020

Programmable editing of a target base in genomic DNA without double-stranded DNA cleavage

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12 December 2020

Rapid "open-source" engineering of customized zinc-finger nucleases for highly efficient gene modification

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12 December 2020

Highly efficient Cas9-mediated gene drive for population modification of the malaria vector mosquito Anopheles stephensi

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12 December 2020

Requirements for double-strand cleavage by chimeric restriction enzymes with zinc finger DNA-recognition domains

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12 December 2020

A ligation-independent cloning technique for high-throughput assembly of transcription activator–like effector genes

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12 December 2020

Hybrid restriction enzymes: zinc finger fusions to Fok I cleavage domain

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12 December 2020

Differential integrity of TALE nuclease genes following adenoviral and lentiviral vector gene transfer into human cells.

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12 December 2020

Exploring strategies for the design of artificial transcription factors: targeting sites proximal to known regulatory regions for the induction of gamma-globin expression and the treatment of sickle cell disease

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12 December 2020

Multiplex genome engineering using CRISPR/Cas systems

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12 December 2020

CRISPR-mediated adaptive immune systems in bacteria and archaea

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12 December 2020

Highly efficient Cas9-mediated transcriptional programming

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12 December 2020

Chemically modified guide RNAs enhance CRISPR-Cas genome editing in human primary cells

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12 December 2020

TALEN-mediated editing of the mouse Y chromosome

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12 December 2020

Identification and characterization of essential genes in the human genome.

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12 December 2020

Efficient delivery of nuclease proteins for genome editing in human stem cells and primary cells

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12 December 2020

Efficient construction of sequence-specific TAL effectors for modulating mammalian transcription

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12 December 2020

Genome-scale transcriptional activation by an engineered CRISPR-Cas9 complex

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12 December 2020

Specific Reactivation of Latent HIV-1 by dCas9-SunTag-VP64-mediated Guide RNA Targeting the HIV-1 Promoter

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12 December 2020

High-frequency off-target mutagenesis induced by CRISPR-Cas nucleases in human cells

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12 December 2020

A Genome-wide CRISPR Screen in Primary Immune Cells to Dissect Regulatory Networks

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12 December 2020

Multi-input CRISPR/Cas genetic circuits that interface host regulatory networks

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12 December 2020

Efficient TALEN-mediated gene knockout in livestock

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12 December 2020

Attenuation of zinc finger nuclease toxicity by small-molecule regulation of protein levels

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12 December 2020

Targeted chromosomal cleavage and mutagenesis in Drosophila using zinc-finger nucleases

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12 December 2020

Epigenome editing by a CRISPR-Cas9-based acetyltransferase activates genes from promoters and enhancers.

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12 December 2020

Functional genetic screens for enhancer elements in the human genome using CRISPR-Cas9.

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12 December 2020

BIOSAFETY. Safeguarding gene drive experiments in the laboratory

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12 December 2020

Site-specific selfish genes as tools for the control and genetic engineering of natural populations.

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12 December 2020

Highly efficient gene knockout in mice and zebrafish with RNA-guided endonucleases

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12 December 2020

RNA-guided human genome engineering via Cas9

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12 December 2020

Targeted gene addition into a specified location in the human genome using designed zinc finger nucleases

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12 December 2020

CRISPR-mediated modular RNA-guided regulation of transcription in eukaryotes

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12 December 2020

CRISPR interference: RNA-directed adaptive immunity in bacteria and archaea

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12 December 2020

Rationally engineered Cas9 nucleases with improved specificity

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12 December 2020

Structures of a CRISPR-Cas9 R-loop complex primed for DNA cleavage

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12 December 2020

Precision genome engineering with programmable DNA-nicking enzymes

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12 December 2020

Efficient generation of a biallelic knockout in pigs using zinc-finger nucleases

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12 December 2020

Targeted methylation and gene silencing of VEGF-A in human cells by using a designed Dnmt3a-Dnmt3L single-chain fusion protein with increased DNA methylation activity

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12 December 2020

A zinc-finger transcriptional activator designed to interact with the gamma-globin gene promoters enhances fetal hemoglobin production in primary human adult erythroblasts

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12 December 2020

Evaluation of TCR Gene Editing Achieved by TALENs, CRISPR/Cas9, and megaTAL Nucleases

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12 December 2020

High-Resolution CRISPR Screens Reveal Fitness Genes and Genotype-Specific Cancer Liabilities.

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12 December 2020

Quantitative analysis of TALE-DNA interactions suggests polarity effects.

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12 December 2020

Genome-Scale CRISPR-Mediated Control of Gene Repression and Activation

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12 December 2020

Targeted chromosomal deletions in human cells using zinc finger nucleases

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12 December 2020

Engineering complex synthetic transcriptional programs with CRISPR RNA scaffolds

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12 December 2020

Cationic lipid-mediated delivery of proteins enables efficient protein-based genome editing in vitro and in vivo

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12 December 2020

Creating a monomeric endonuclease TALE-I-SceI with high specificity and low genotoxicity in human cells

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12 December 2020

Cpf1 is a single RNA-guided endonuclease of a class 2 CRISPR-Cas system

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12 December 2020

Repurposing CRISPR as an RNA-guided platform for sequence-specific control of gene expression

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12 December 2020

Drug-inducible and simultaneous regulation of endogenous genes by single-chain nuclear receptor-based zinc-finger transcription factor gene switches

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12 December 2020

A Programmable Dual-RNA-Guided DNA Endonuclease in Adaptive Bacterial Immunity

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12 December 2020

In vivo gene editing in dystrophic mouse muscle and muscle stem cells

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12 December 2020

Targeted integration in rat and mouse embryos with zinc-finger nucleases

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12 December 2020

Introduction of double-strand breaks into the genome of mouse cells by expression of a rare-cutting endonuclease

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12 December 2020

Building zinc fingers by selection: toward a therapeutic application

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12 December 2020

Regulation of endogenous human gene expression by ligand-inducible TALE transcription factors.

1 reference

12 December 2020

Improved cell-penetrating zinc-finger nuclease proteins for precision genome engineering

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12 December 2020

A bistable genetic switch based on designable DNA-binding domains

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12 December 2020

Revealing off-target cleavage specificities of zinc-finger nucleases by in vitro selection

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12 December 2020

Genome editing. The mutagenic chain reaction: a method for converting heterozygous to homozygous mutations

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12 December 2020

10.1101/CSHPERSPECT.A023754

Identifiers

DOI

1 reference

8 September 2017

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1 reference