(Q36231119)

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The repair of DNA damages/modifications during the maturation of the immune system: lessons from human primary immunodeficiency disorders and animal models.

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5 January 2020

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The repair of DNA damages/modifications during the maturation of the immune system: lessons from human primary immunodeficiency disorders and animal models (English)

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5 January 2020

Jean-Pierre de Villartay

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Dietke Buck

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5 January 2020

Françoise le Deist

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1 January 2005

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Advances in Immunology

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237-295

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Europe PubMed Central

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5 January 2020

The DNA double-strand break response in the nervous system

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987007-5

7 January 2021

based on heuristic

inferred from DOI database lookup

p53 controls both the G2/M and the G1 cell cycle checkpoints and mediates reversible growth arrest in human fibroblasts

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987007-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Transposition mediated by RAG1 and RAG2 and its implications for the evolution of the immune system

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987007-5

7 January 2021

based on heuristic

inferred from DOI database lookup

CD40 ligand gene defects responsible for X-linked hyper-IgM syndrome

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987007-5

7 January 2021

based on heuristic

inferred from DOI database lookup

The CD40 ligand, gp39, is defective in activated T cells from patients with X-linked hyper-IgM syndrome

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987007-5

7 January 2021

based on heuristic

inferred from DOI database lookup

DNA damage activates ATM through intermolecular autophosphorylation and dimer dissociation

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987007-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Altered somatic hypermutation and reduced class-switch recombination in exonuclease 1-mutant mice

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987007-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Mutations in the DNA ligase I gene of an individual with immunodeficiencies and cellular hypersensitivity to DNA-damaging agents

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987007-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Mammalian G1- and S-phase checkpoints in response to DNA damage

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987007-5

7 January 2021

based on heuristic

inferred from DOI database lookup

The mechanism and regulation of chromosomal V(D)J recombination

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987007-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Radiosensitivity in ataxia-telangiectasia: anomalies in radiation-induced cell cycle delay

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987007-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Ataxia-telangiectasia: phenotype/genotype studies of ATM protein expression, mutations, and radiosensitivity

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987007-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Uracil DNA glycosylase activity is dispensable for immunoglobulin class switch

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987007-5

7 January 2021

based on heuristic

inferred from DOI database lookup

De novo protein synthesis is required for activation-induced cytidine deaminase-dependent DNA cleavage in immunoglobulin class switch recombination

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987007-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Somatic hypermutation in the absence of DNA-dependent protein kinase catalytic subunit (DNA-PK(cs)) or recombination-activating gene (RAG)1 activity

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987007-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Cutting edge: DNA polymerases mu and lambda are dispensable for Ig gene hypermutation

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987007-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Influence of severe combined immunodeficiency phenotype on the outcome of HLA non-identical, T-cell–depleted bone marrow transplantationA retrospective European survey from the European Group for Bone Marrow Transplantation and the European Society

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987007-5

7 January 2021

based on heuristic

inferred from DOI database lookup

scid mutation in mice confers hypersensitivity to ionizing radiation and a deficiency in DNA double-strand break repair

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987007-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Identification of a nonsense mutation in the carboxyl-terminal region of DNA-dependent protein kinase catalytic subunit in the scid mouse

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987007-5

7 January 2021

based on heuristic

inferred from DOI database lookup

V(D)J recombination in Ku86-deficient mice: distinct effects on coding, signal, and hybrid joint formation

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987007-5

7 January 2021

based on heuristic

inferred from DOI database lookup

DNA-dependent protein kinase activity is not required for immunoglobulin class switching

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987007-5

7 January 2021

based on heuristic

inferred from DOI database lookup

The SCID mouse mutant: definition, characterization, and potential uses

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987007-5

7 January 2021

based on heuristic

inferred from DOI database lookup

scid cells are deficient in Ku and replication protein A phosphorylation by the DNA-dependent protein kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987007-5

7 January 2021

based on heuristic

inferred from DOI database lookup

A recombinase diversified: new functions of the RAG proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987007-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Activation-induced cytidine deaminase deaminates deoxycytidine on single-stranded DNA but requires the action of RNase

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987007-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Activation-induced cytosine deaminase (AID) is actively exported out of the nucleus but retained by the induction of DNA breaks

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987007-5

7 January 2021

based on heuristic

inferred from DOI database lookup

DNA Double-Strand Breaks in Immunoglobulin Genes Undergoing Somatic Hypermutation

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987007-5

7 January 2021

based on heuristic

inferred from DOI database lookup

DNA double-strand breaks: prior to but not sufficient in targeting hypermutation

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987007-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Somatic hypermutation does not require Rad54 and Rad54B-mediated homologous recombination

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987007-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Essential and dispensable roles of ATR in cell cycle arrest and genome maintenance

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987007-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Absence of DNA ligase IV protein in XR-1 cells: evidence for stabilization by XRCC4.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987007-5

7 January 2021

based on heuristic

inferred from DOI database lookup

ATM phosphorylates histone H2AX in response to DNA double-strand breaks

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987007-5

7 January 2021

based on heuristic

inferred from DOI database lookup

From BRCA1 to RAP1: a widespread BRCT module closely associated with DNA repair

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987007-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Metallo-beta-lactamase fold within nucleic acids processing enzymes: the beta-CASP family

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987007-5

7 January 2021

based on heuristic

inferred from DOI database lookup

The hMre11/hRad50 protein complex and Nijmegen breakage syndrome: linkage of double-strand break repair to the cellular DNA damage response

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987007-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Mismatch repair co-opted by hypermutation.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987007-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Ku80 is required for immunoglobulin isotype switching

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987007-5

7 January 2021

based on heuristic

inferred from DOI database lookup

The block in immunoglobulin class switch recombination caused by activation-induced cytidine deaminase deficiency occurs prior to the generation of DNA double strand breaks in switch mu region

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987007-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Increased radiosensitivity of granulocyte macrophage colony-forming units and skin fibroblasts in human autosomal recessive severe combined immunodeficiency

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987007-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Genomic instability in mice lacking histone H2AX

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987007-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Mammalian Chk2 is a downstream effector of the ATM-dependent DNA damage checkpoint pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987007-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Replication protein A interacts with AID to promote deamination of somatic hypermutation targets

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987007-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Transcription-targeted DNA deamination by the AID antibody diversification enzyme

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987007-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Response to RAG-mediated VDJ cleavage by NBS1 and gamma-H2AX

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987007-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Chk1 Kinase Negatively Regulates Mitotic Function of Cdc25A Phosphatase through 14-3-3 Binding

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987007-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Variable deletion and duplication at recombination junction ends: implication for staggered double-strand cleavage in class-switch recombination

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987007-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Ataxia-telangiectasia, an evolving phenotype

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987007-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Reduced switching in SCID B cells is associated with altered somatic mutation of recombined S regions

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987007-5

7 January 2021

based on heuristic

inferred from DOI database lookup

On the nature of a defect in cells from individuals with ataxia-telangiectasia

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987007-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Mammalian DNA double-strand break repair protein XRCC4 interacts with DNA ligase IV

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987007-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Nonhomologous end joining and V(D)J recombination require an additional factor

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987007-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Expansion of the zinc metallo-hydrolase family of the beta-lactamase fold

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987007-5

7 January 2021

based on heuristic

inferred from DOI database lookup

CD40 ligand expression deficiency in a female carrier of the X-linked hyper-IgM syndrome as a result of X chromosome lyonization

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987007-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Human and animal models of V(D)J recombination deficiency

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987007-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Decreased Frequency of Somatic Hypermutation and Impaired Affinity Maturation but Intact Germinal Center Formation in Mice Expressing Antisense RNA to DNA Polymerase

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987007-5

7 January 2021

based on heuristic

inferred from DOI database lookup

AID mediates hypermutation by deaminating single stranded DNA.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987007-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Evidence for replicative repair of DNA double-strand breaks leading to oncogenic translocation and gene amplification

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987007-5

7 January 2021

based on heuristic

inferred from DOI database lookup

CD40 ligand mutations in X-linked immunodeficiency with hyper-IgM

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987007-5

7 January 2021

based on heuristic

inferred from DOI database lookup

De novo protein synthesis is required for the activation-induced cytidine deaminase function in class-switch recombination

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987007-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Human models of inherited immunoglobulin class switch recombination and somatic hypermutation defects (hyper-IgM syndromes).

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987007-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Induction by anti-CD40 antibody or soluble CD40 ligand and cytokines of IgG, IgA and IgE production by B cells from patients with X-linked hyper IgM syndrome

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987007-5

7 January 2021

based on heuristic

inferred from DOI database lookup

DNA-PK, ATM and ATR as sensors of DNA damage: variations on a theme?

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987007-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Deficiency in Msh2 affects the efficiency and local sequence specificity of immunoglobulin class-switch recombination: parallels with somatic hypermutation.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987007-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Mice reconstituted with DNA polymerase beta-deficient fetal liver cells are able to mount a T cell-dependent immune response and mutate their Ig genes normally

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987007-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Critical roles of activation-induced cytidine deaminase in the homeostasis of gut flora

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987007-5

7 January 2021

based on heuristic

inferred from DOI database lookup

DNA polymerase eta is involved in hypermutation occurring during immunoglobulin class switch recombination.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987007-5

7 January 2021

based on heuristic

inferred from DOI database lookup

DNA repair: The Nijmegen breakage syndrome protein

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987007-5

7 January 2021

based on heuristic

inferred from DOI database lookup

DNA double strand break repair and chromosomal translocation: lessons from animal models

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987007-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Mutations of CD40 gene cause an autosomal recessive form of immunodeficiency with hyper IgM.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987007-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Severe combined immunodeficiencies (SCID)

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987007-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Late embryonic lethality and impaired V(D)J recombination in mice lacking DNA ligase IV

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987007-5

7 January 2021

based on heuristic

inferred from DOI database lookup

The scid mutation in mice causes a general defect in DNA repair

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987007-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Phosphorylation of histone H2AX and activation of Mre11, Rad50, and Nbs1 in response to replication-dependent DNA double-strand breaks induced by mammalian DNA topoisomerase I cleavage complexes.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987007-5

7 January 2021

based on heuristic

inferred from DOI database lookup

A targeted DNA-PKcs-null mutation reveals DNA-PK-independent functions for KU in V(D)J recombination

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987007-5

7 January 2021

based on heuristic

inferred from DOI database lookup

V(D)J recombination: RAG proteins, repair factors, and regulation

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987007-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Analysis of DNA ligase IV mutations found in LIG4 syndrome patients: the impact of two linked polymorphisms

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987007-5

7 January 2021

based on heuristic

inferred from DOI database lookup

MDC1 is required for the intra-S-phase DNA damage checkpoint

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987007-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Activity of DNA ligase IV stimulated by complex formation with XRCC4 protein in mammalian cells

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987007-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Requirement for an interaction of XRCC4 with DNA ligase IV for wild-type V(D)J recombination and DNA double-strand break repair in vivo.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987007-5

7 January 2021

based on heuristic

inferred from DOI database lookup

DNA ligase IV binds to XRCC4 via a motif located between rather than within its BRCT domains.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987007-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Partners and pathwaysrepairing a double-strand break.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987007-5

7 January 2021

based on heuristic

inferred from DOI database lookup

DNA mismatch repair and genetic instability

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987007-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Normal V(D)J recombination in cells from patients with Nijmegen breakage syndrome

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987007-5

7 January 2021

based on heuristic

inferred from DOI database lookup

A link between double-strand break-related repair and V(D)J recombination: the scid mutation

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987007-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Assembly of a 12/23 paired signal complex: a critical control point in V(D)J recombination

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987007-5

7 January 2021

based on heuristic

inferred from DOI database lookup

DNA transposition by the RAG1 and RAG2 proteins: a possible source of oncogenic translocations.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987007-5

7 January 2021

based on heuristic

inferred from DOI database lookup

AID: how does it aid antibody diversity?

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987007-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Distinct functional domains of Nbs1 modulate the timing and magnitude of ATM activation after low doses of ionizing radiation

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987007-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Hyper-IgM syndrome type 4 with a B lymphocyte-intrinsic selective deficiency in Ig class-switch recombination

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987007-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Human uracil-DNA glycosylase deficiency associated with profoundly impaired immunoglobulin class-switch recombination

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987007-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Activation-induced cytidine deaminase shuttles between nucleus and cytoplasm like apolipoprotein B mRNA editing catalytic polypeptide 1

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987007-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Healing the wounds inflicted by sleeping beauty transposition by double-strand break repair in mammalian somatic cells.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987007-5

7 January 2021

based on heuristic

inferred from DOI database lookup

In situ studies of the primary immune response to (4-hydroxy-3-nitrophenyl)acetyl. II. A common clonal origin for periarteriolar lymphoid sheath-associated foci and germinal centers

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987007-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Hypermutation of immunoglobulin genes in memory B cells of DNA repair-deficient mice

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987007-5

7 January 2021

based on heuristic

inferred from DOI database lookup

DNA-PKcs: a T-cell tumour suppressor encoded at the mouse scid locus

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987007-5

7 January 2021

based on heuristic

inferred from DOI database lookup

mRNA sequences define an unusually restricted IgG response to 2-phenyloxazolone and its early diversification.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987007-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Cell-cycle-dependent and ATM-independent expression of human Chk1 kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987007-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Targeted disruption of NBS1 reveals its roles in mouse development and DNA repair

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987007-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Cancer-susceptibility genes. Gatekeepers and caretakers

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987007-5

7 January 2021

based on heuristic

inferred from DOI database lookup

DNA-dependent kinase (p350) as a candidate gene for the murine SCID defect

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987007-5

7 January 2021

based on heuristic

inferred from DOI database lookup

V(D)J recombination and ataxia-telangiectasia: a review

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987007-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Human immunoglobulin (Ig)M+IgD+ peripheral blood B cells expressing the CD27 cell surface antigen carry somatically mutated variable region genes: CD27 as a general marker for somatically mutated (memory) B cells

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987007-5

7 January 2021

based on heuristic

inferred from DOI database lookup

NBS1 localizes to gamma-H2AX foci through interaction with the FHA/BRCT domain

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987007-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Novel Artemis gene mutations of radiosensitive severe combined immunodeficiency in Japanese families

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987007-5

7 January 2021

based on heuristic

inferred from DOI database lookup

PMS2-deficiency diminishes hypermutation of a lambda1 transgene in young but not older mice

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987007-5

7 January 2021

based on heuristic

inferred from DOI database lookup

BRCA1 protein products ... Functional motifs...

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987007-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Defective expression of T-cell CD40 ligand causes X-linked immunodeficiency with hyper-IgM

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987007-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Cellular origin of human B-cell lymphomas.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987007-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Outcome of hematopoietic stem cell transplantation in hyper-IgM syndrome caused by CD40 deficiency

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987007-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Oral and genital ulceration: a unique presentation of immunodeficiency in Athabascan-speaking American Indian children with severe combined immunodeficiency

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987007-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Delineation of the role of the Mre11 complex in class switch recombination.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987007-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Germinal center founder cells display propensity for apoptosis before onset of somatic mutation

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987007-5

7 January 2021

based on heuristic

inferred from DOI database lookup

RAG proteins shepherd double-strand breaks to a specific pathway, suppressing error-prone repair, but RAG nicking initiates homologous recombination.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987007-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Direct activation of the ATM protein kinase by the Mre11/Rad50/Nbs1 complex

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987007-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Role of ATM in oxidative stress-mediated c-Jun phosphorylation in response to ionizing radiation and CdCl2.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987007-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Mutations at the ataxia-telangiectasia locus and clinical phenotypes of A-T patients

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987007-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Ku70: a candidate tumor suppressor gene for murine T cell lymphoma

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987007-5

7 January 2021

based on heuristic

inferred from DOI database lookup

The gene for severe combined immunodeficiency disease in Athabascan-speaking Native Americans is located on chromosome 10p.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987007-5

7 January 2021

based on heuristic

inferred from DOI database lookup

A founder mutation in Artemis, an SNM1-like protein, causes SCID in Athabascan-speaking Native Americans

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987007-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Rad51 expression and localization in B cells carrying out class switch recombination

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987007-5

7 January 2021

based on heuristic

inferred from DOI database lookup

The XRCC4 gene encodes a novel protein involved in DNA double-strand break repair and V(D)J recombination

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987007-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Examination of Msh6- and Msh3-deficient mice in class switching reveals overlapping and distinct roles of MutS homologues in antibody diversification

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987007-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Critical role for Atm in suppressing V(D)J recombination-driven thymic lymphoma

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987007-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Within germinal centers, isotype switching of immunoglobulin genes occurs after the onset of somatic mutation

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987007-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Ig gene somatic hypermutation in mice defective for DNA polymerase delta proofreading

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987007-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Nuclear localization of Cdc25 is regulated by DNA damage and a 14-3-3 protein

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987007-5

7 January 2021

based on heuristic

inferred from DOI database lookup

MDC1 is coupled to activated CHK2 in mammalian DNA damage response pathways

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987007-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Hairpin opening and overhang processing by an Artemis/DNA-dependent protein kinase complex in nonhomologous end joining and V(D)J recombination

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987007-5

7 January 2021

based on heuristic

inferred from DOI database lookup

IgH class switch recombination to IgG1 in DNA-PKcs-deficient B cells

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987007-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Ku70 is required for late B cell development and immunoglobulin heavy chain class switching

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987007-5

7 January 2021

based on heuristic

inferred from DOI database lookup

53BP1 links DNA damage-response pathways to immunoglobulin heavy chain class-switch recombination.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987007-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Genetic heterogeneity for a Nijmegen breakage‐like syndrome

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987007-5

7 January 2021

based on heuristic

inferred from DOI database lookup

V(D)J-mediated translocations in lymphoid neoplasms: a functional assessment of genomic instability by cryptic sites.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987007-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Msh2 ATPase activity is essential for somatic hypermutation at a-T basepairs and for efficient class switch recombination

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987007-5

7 January 2021

based on heuristic

inferred from DOI database lookup

A role for Msh6 but not Msh3 in somatic hypermutation and class switch recombination

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987007-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Positional cloning of the gene for Nijmegen breakage syndrome

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987007-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Cleavage at a V(D)J recombination signal requires only RAG1 and RAG2 proteins and occurs in two steps.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987007-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Somatic hypermutation is limited by CRM1-dependent nuclear export of activation-induced deaminase

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987007-5

7 January 2021

based on heuristic

inferred from DOI database lookup

129-derived strains of mice are deficient in DNA polymerase iota and have normal immunoglobulin hypermutation

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987007-5

7 January 2021

based on heuristic

inferred from DOI database lookup

The essential cofactor TRRAP recruits the histone acetyltransferase hGCN5 to c-Myc

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987007-5

7 January 2021

based on heuristic

inferred from DOI database lookup

The DNA-dependent protein kinase: the director at the end.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987007-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Effect of HIV integrase inhibitors on the RAG1/2 recombinase

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987007-5

7 January 2021

based on heuristic

inferred from DOI database lookup

A unified view of the DNA-damage checkpoint

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987007-5

7 January 2021

based on heuristic

inferred from DOI database lookup

In vivo transposition mediated by V(D)J recombinase in human T lymphocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987007-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Mutations in activation-induced cytidine deaminase in patients with hyper IgM syndrome

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987007-5

7 January 2021

based on heuristic

inferred from DOI database lookup

RAG-1-deficient mice have no mature B and T lymphocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987007-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Artemis, a novel DNA double-strand break repair/V(D)J recombination protein, is mutated in human severe combined immune deficiency.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987007-5

7 January 2021

based on heuristic

inferred from DOI database lookup

A new gene involved in DNA double-strand break repair and V(D)J recombination is located on human chromosome 10p

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987007-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Partial T and B lymphocyte immunodeficiency and predisposition to lymphoma in patients with hypomorphic mutations in Artemis

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987007-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Class switch recombination and hypermutation require activation-induced cytidine deaminase (AID), a potential RNA editing enzyme

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987007-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Specific expression of activation-induced cytidine deaminase (AID), a novel member of the RNA-editing deaminase family in germinal center B cells

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987007-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Transcription-coupled events associating with immunoglobulin switch region chromatin

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987007-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Lack of detectable defect in DNA double-strand break repair and DNA-dependent protein kinase activity in radiosensitive human severe combined immunodeficiency fibroblasts

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987007-5

7 January 2021

based on heuristic

inferred from DOI database lookup

A human severe combined immunodeficiency (SCID) condition with increased sensitivity to ionizing radiations and impaired V(D)J rearrangements defines a new DNA recombination/repair deficiency

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987007-5

7 January 2021

based on heuristic

inferred from DOI database lookup

TRRAP-dependent and TRRAP-independent transcriptional activation by Myc family oncoproteins

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987007-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Gene-targeted mice lacking the Ung uracil-DNA glycosylase develop B-cell lymphomas

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987007-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Radiosensitive SCID patients with Artemis gene mutations show a complete B-cell differentiation arrest at the pre-B-cell receptor checkpoint in bone marrow.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987007-5

7 January 2021

based on heuristic

inferred from DOI database lookup

DNA ligase IV mutations identified in patients exhibiting developmental delay and immunodeficiency

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987007-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Bone marrow transplantation for T-B- severe combined immunodeficiency disease in Athabascan-speaking native Americans

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987007-5

7 January 2021

based on heuristic

inferred from DOI database lookup

RAG-1 and RAG-2, adjacent genes that synergistically activate V(D)J recombination

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987007-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Constitutive expression of AID leads to tumorigenesis

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987007-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Alternative end joining during switch recombination in patients with ataxia-telangiectasia

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987007-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Functional and biochemical dissection of the structure-specific nuclease ARTEMIS

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987007-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Cell-cycle-regulated DNA double-stranded breaks in somatic hypermutation of immunoglobulin genes

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987007-5

7 January 2021

based on heuristic

inferred from DOI database lookup

The activation-induced deaminase functions in a postcleavage step of the somatic hypermutation process

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987007-5

7 January 2021

based on heuristic

inferred from DOI database lookup

DNA-PK is activated by nucleosomes and phosphorylates H2AX within the nucleosomes in an acetylation-dependent manner

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987007-5

7 January 2021

based on heuristic

inferred from DOI database lookup

A critical role for histone H2AX in recruitment of repair factors to nuclear foci after DNA damage

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987007-5

7 January 2021

based on heuristic

inferred from DOI database lookup

NFBD1, like 53BP1, is an early and redundant transducer mediating Chk2 phosphorylation in response to DNA damage

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987007-5

7 January 2021

based on heuristic

inferred from DOI database lookup

V(D)J recombination in mammalian cell mutants defective in DNA double-strand break repair

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987007-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Sensing of intermediates in V(D)J recombination by ATM.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987007-5

7 January 2021

based on heuristic

inferred from DOI database lookup

AID is required to initiate Nbs1/gamma-H2AX focus formation and mutations at sites of class switching

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987007-5

7 January 2021

based on heuristic

inferred from DOI database lookup

AID mutates E. coli suggesting a DNA deamination mechanism for antibody diversification

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987007-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Speculations on ataxia-telangiectasia: defective regulation of the immunoglobulin gene superfamily

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987007-5

7 January 2021

based on heuristic

inferred from DOI database lookup

ATAXIA-TELANGIECTASIA. ITS ASSOCIATION WITH A DEFECTIVE THYMUS, IMMUNOLOGICAL-DEFICIENCY DISEASE, AND MALIGNANCY

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987007-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Recombinase-activating gene (RAG) 2-mediated V(D)J recombination is not essential for tumorigenesis in Atm-deficient mice

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987007-5

7 January 2021

based on heuristic

inferred from DOI database lookup

The cellular response to DNA double-strand breaks: defining the sensors and mediators

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987007-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Processive AID-catalysed cytosine deamination on single-stranded DNA simulates somatic hypermutation

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987007-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Increased hypermutation at G and C nucleotides in immunoglobulin variable genes from mice deficient in the MSH2 mismatch repair protein

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987007-5

7 January 2021

based on heuristic

inferred from DOI database lookup

The DNA crosslink-induced S-phase checkpoint depends on ATR-CHK1 and ATR-NBS1-FANCD2 pathways

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987007-5

7 January 2021

based on heuristic

inferred from DOI database lookup

An instance of clinical radiation morbidity and cellular radiosensitivity, not associated with ataxia-telangiectasia

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987007-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Phosphorylation of Artemis following irradiation-induced DNA damage

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987007-5

7 January 2021

based on heuristic

inferred from DOI database lookup

The metallo-beta-lactamase/beta-CASP domain of Artemis constitutes the catalytic core for V(D)J recombination

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987007-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Ku80 is required for addition of N nucleotides to V(D)J recombination junctions by terminal deoxynucleotidyl transferase

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987007-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Clinical, immunologic and genetic analysis of 29 patients with autosomal recessive hyper-IgM syndrome due to Activation-Induced Cytidine Deaminase deficiency

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987007-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Hot spot focusing of somatic hypermutation in MSH2-deficient mice suggests two stages of mutational targeting

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987007-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Immunoglobulin isotype switching is inhibited and somatic hypermutation perturbed in UNG-deficient mice

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987007-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Analysis of the V(D)J recombination efficiency at lymphoid chromosomal translocation breakpoints

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987007-5

7 January 2021

based on heuristic

inferred from DOI database lookup

A non-B-DNA structure at the Bcl-2 major breakpoint region is cleaved by the RAG complex

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987007-5

7 January 2021

based on heuristic

inferred from DOI database lookup

AID is required for c-myc/IgH chromosome translocations in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987007-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Transcription enhances AID-mediated cytidine deamination by exposing single-stranded DNA on the nontemplate strand

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987007-5

7 January 2021

based on heuristic

inferred from DOI database lookup

DNA double strand breaks (DSB) and non-homologous end joining (NHEJ) pathways in human leukemia

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987007-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Induction of RNA-stabilized DMA conformers by transcription of an immunoglobulin switch region

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987007-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Histone H2A variants H2AX and H2AZ

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987007-5

7 January 2021

based on heuristic

inferred from DOI database lookup

H2AX is required for recombination between immunoglobulin switch regions but not for intra-switch region recombination or somatic hypermutation

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987007-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Activation-induced cytidine deaminase (AID) deficiency causes the autosomal recessive form of the Hyper-IgM syndrome (HIGM2)

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987007-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Identification of a defect in DNA ligase IV in a radiosensitive leukaemia patient

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987007-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Cellular and biochemical impact of a mutation in DNA ligase IV conferring clinical radiosensitivity

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987007-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Genetic variants of NHEJ DNA ligase IV can affect the risk of developing multiple myeloma, a tumour characterised by aberrant class switch recombination

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987007-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Megabase chromatin domains involved in DNA double-strand breaks in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987007-5

7 January 2021

based on heuristic

inferred from DOI database lookup

DNA double-stranded breaks induce histone H2AX phosphorylation on serine 139

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987007-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Defective DNA repair and increased genomic instability in Artemis-deficient murine cells

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987007-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Artemis and p53 cooperate to suppress oncogenic N-myc amplification in progenitor B cells.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987007-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Leaky Scid phenotype associated with defective V(D)J coding end processing in Artemis-deficient mice

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987007-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Restraining the V(D)J recombinase

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987007-5

7 January 2021

based on heuristic

inferred from DOI database lookup

VDJ recombination: a transposase goes to work

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987007-5

7 January 2021

based on heuristic

inferred from DOI database lookup

V(D)J recombination: broken DNA molecules with covalently sealed (hairpin) coding ends in scid mouse thymocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987007-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Staggered AID-dependent DNA double strand breaks are the predominant DNA lesions targeted to S mu in Ig class switch recombination

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987007-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Evidence that polyadenylation factor CPSF-73 is the mRNA 3' processing endonuclease.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987007-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Ablation of XRCC2/3 transforms immunoglobulin V gene conversion into somatic hypermutation

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987007-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Molecular mechanisms of mammalian DNA repair and the DNA damage checkpoints

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987007-5

7 January 2021

based on heuristic

inferred from DOI database lookup

The V(D)J recombination activating gene, RAG-1.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987007-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Double-strand signal sequence breaks in V(D)J recombination are blunt, 5'-phosphorylated, RAG-dependent, and cell cycle regulated

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987007-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Structure of nonhairpin coding-end DNA breaks in cells undergoing V(D)J recombination

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987007-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Does artemis end the hunt for the hairpin-opening activity in V(D)J recombination?

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987007-5

7 January 2021

based on heuristic

inferred from DOI database lookup

The interaction of DNA mismatch repair proteins with human exonuclease I

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987007-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Reduced isotype switching in splenic B cells from mice deficient in mismatch repair enzymes

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987007-5

7 January 2021

based on heuristic

inferred from DOI database lookup

RAG mutations in human B cell-negative SCID.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987007-5

7 January 2021

based on heuristic

inferred from DOI database lookup

NFBD1, a novel nuclear protein with signature motifs of FHA and BRCT, and an internal 41-amino acid repeat sequence, is an early participant in DNA damage response

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987007-5

7 January 2021

based on heuristic

inferred from DOI database lookup

ATM and related protein kinases: safeguarding genome integrity

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987007-5

7 January 2021

based on heuristic

inferred from DOI database lookup

RAG-2-deficient mice lack mature lymphocytes owing to inability to initiate V(D)J rearrangement

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987007-5

7 January 2021

based on heuristic

inferred from DOI database lookup

The influence of transcriptional orientation on endogenous switch region function

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987007-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Crystal structure of an Xrcc4-DNA ligase IV complex

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987007-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Impact of DNA ligase IV on the fidelity of end joining in human cells

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987007-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Human activation-induced cytidine deaminase causes transcription-dependent, strand-biased C to U deaminations

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987007-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Severe combined immunodeficiency: a retrospective single-center study of clinical presentation and outcome in 117 patients

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987007-5

7 January 2021

based on heuristic

inferred from DOI database lookup

The DNA double-strand break repair gene hMRE11 is mutated in individuals with an ataxia-telangiectasia-like disorder

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987007-5

7 January 2021

based on heuristic

inferred from DOI database lookup

MDC1 is a mediator of the mammalian DNA damage checkpoint

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987007-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Mortality rates among carriers of ataxia-telangiectasia mutant alleles

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987007-5

7 January 2021

based on heuristic

inferred from DOI database lookup

AID mutant analyses indicate requirement for class-switch-specific cofactors

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987007-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Targeted disruption of the catalytic subunit of the DNA-PK gene in mice confers severe combined immunodeficiency and radiosensitivity

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987007-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Impairment of V(D)J recombination in double-strand break repair mutants

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987007-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Nijmegen breakage syndrome gene, NBS1, and molecular links to factors for genome stability

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987007-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Ataxia-telangiectasia-like disorder (ATLD)-its clinical presentation and molecular basis

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987007-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Structure and function of mammalian DNA ligases

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987007-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Somatic generation of antibody diversity

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987007-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Requirement of the MRN complex for ATM activation by DNA damage

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987007-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Genomic Organization of the ATM gene

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987007-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Decreased immunoglobulin class switching in Nijmegen Breakage syndrome due to the DNA repair defect.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987007-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Nibrin, a novel DNA double-strand break repair protein, is mutated in Nijmegen breakage syndrome

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987007-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Severe attenuation of the B cell immune response in Msh2-deficient mice

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987007-5

7 January 2021

based on heuristic

inferred from DOI database lookup

DNA damage: Chk1 and Cdc25, more than meets the eye.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987007-5

7 January 2021

based on heuristic

inferred from DOI database lookup

53BP1, a mediator of the DNA damage checkpoint

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987007-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Metallo-beta-lactamase: structure and mechanism

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987007-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Histone H2AX is phosphorylated in an ATR-dependent manner in response to replicational stress

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987007-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Accumulation of Checkpoint Protein 53BP1 at DNA Breaks Involves Its Binding to Phosphorylated Histone H2AX

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987007-5

7 January 2021

based on heuristic

inferred from DOI database lookup

53BP1 is required for class switch recombination

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987007-5

7 January 2021

based on heuristic

inferred from DOI database lookup

A new chromosomal instability disorder: the Nijmegen breakage syndrome

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987007-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Human blood IgM "memory" B cells are circulating splenic marginal zone B cells harboring a prediversified immunoglobulin repertoire

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987007-5

7 January 2021

based on heuristic

inferred from DOI database lookup

CD40-CD40L independent Ig gene hypermutation suggests a second B cell diversification pathway in humans

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987007-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Somatic hypermutation in MutS homologue (MSH)3-, MSH6-, and MSH3/MSH6-deficient mice reveals a role for the MSH2-MSH6 heterodimer in modulating the base substitution pattern

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987007-5

7 January 2021

based on heuristic

inferred from DOI database lookup

A murine model of Nijmegen breakage syndrome

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987007-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Altered spectra of hypermutation in antibodies from mice deficient for the DNA mismatch repair protein PMS2

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987007-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Chk1 mediates S and G2 arrests through Cdc25A degradation in response to DNA-damaging agents

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987007-5

7 January 2021

based on heuristic

inferred from DOI database lookup

NFBD1/MDC1 regulates ionizing radiation-induced focus formation by DNA checkpoint signaling and repair factors

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987007-5

7 January 2021

based on heuristic

inferred from DOI database lookup

A DNA damage-regulated BRCT-containing protein, TopBP1, is required for cell survival

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987007-5

7 January 2021

based on heuristic

inferred from DOI database lookup

The role of polymerase eta in somatic hypermutation determined by analysis of mutations in a patient with xeroderma pigmentosum variant

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987007-5

7 January 2021

based on heuristic

inferred from DOI database lookup

R-loops at immunoglobulin class switch regions in the chromosomes of stimulated B cells

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987007-5

7 January 2021

based on heuristic

inferred from DOI database lookup

The translesion DNA polymerase zeta plays a major role in Ig and bcl-6 somatic hypermutation.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987007-5

7 January 2021

based on heuristic

inferred from DOI database lookup

AID-dependent generation of resected double-strand DNA breaks and recruitment of Rad52/Rad51 in somatic hypermutation

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987007-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Absence of DNA polymerase eta reveals targeting of C mutations on the nontranscribed strand in immunoglobulin switch regions

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987007-5

7 January 2021

based on heuristic

inferred from DOI database lookup

DNA polymerase eta is an A-T mutator in somatic hypermutation of immunoglobulin variable genes

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987007-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Unrepaired DNA breaks in p53-deficient cells lead to oncogenic gene amplification subsequent to translocations.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987007-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Targeted disruption of the Nijmegen breakage syndrome gene NBS1 leads to early embryonic lethality in mice.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987007-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Identifiers

10.1016/S0065-2776(05)87007-5

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16102576%20AND%20SRC:MED&resulttype=core&format=json

5 January 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16102576%20AND%20SRC:MED&resulttype=core&format=json

5 January 2020

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