(Q38264793)

1 September 2017

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title

Autophagy in neuronal cells: general principles and physiological and pathological functions (English)

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1 September 2017

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4

Eeva-Liisa Eskelinen

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Taina Suntio

object named as

Taina Suntio

series ordinal

2

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author name string

Markus Damme

series ordinal

1

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PubMed ID

25367385

1 September 2017

Paul Saftig

series ordinal

3

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1 September 2017

4 November 2014

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1 September 2017

Acta Neuropathologica

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1 September 2017

129

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1 September 2017

3

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1 September 2017

337-362

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https://scigraph.springernature.com/pub.10.1007/s00401-014-1361-4

1 September 2017

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cites work

Early otic development depends on autophagy for apoptotic cell clearance and neural differentiation.

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1361-4

Autophagy induction by trehalose counteracts cellular prion infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1361-4

Development and characterization of a new Parkinson's disease model resulting from impaired autophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1361-4

Role of AMPK-mTOR-Ulk1/2 in the regulation of autophagy: cross talk, shortcuts, and feedbacks

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1361-4

Short-term fasting induces profound neuronal autophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1361-4

Autophagosome formation from membrane compartments enriched in phosphatidylinositol 3-phosphate and dynamically connected to the endoplasmic reticulum

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1361-4

Modulation of mitochondrial function and autophagy mediates carnosine neuroprotection against ischemic brain damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1361-4

IGF-I stimulates Rab7-RILP interaction during neuronal autophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1361-4

Lysosomal disorders: from storage to cellular damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1361-4

Autophagy negatively regulates early axon growth in cortical neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1361-4

The chaperone-mediated autophagy receptor organizes in dynamic protein complexes at the lysosomal membrane

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1361-4

Identification of regulators of chaperone-mediated autophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1361-4

p62, Ref(2)P and ubiquitinated proteins are conserved markers of neuronal aging, aggregate formation and progressive autophagic defects.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1361-4

Mitochondrial autophagy in neural function, neurodegenerative disease, neuron cell death, and aging

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1361-4

Parkin-mediated ubiquitination of mutant glucocerebrosidase leads to competition with its substrates PARIS and ARTS

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1361-4

The role of membrane-trafficking small GTPases in the regulation of autophagy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1361-4

p62/SQSTM1 forms protein aggregates degraded by autophagy and has a protective effect on huntingtin-induced cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1361-4

Emerging regulation and functions of autophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1361-4

Regulation of TDP-43 aggregation by phosphorylation and p62/SQSTM1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1361-4

The mitochondrial-lysosomal axis theory of aging: accumulation of damaged mitochondria as a result of imperfect autophagocytosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1361-4

Eukaryotic stress granules are cleared by autophagy and Cdc48/VCP function

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1361-4

Fine structure of nerve fibers and growth cones of isolated sympathetic neurons in culture

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1361-4

Hydrogen peroxide induces autophagic cell death in C6 glioma cells via BNIP3-mediated suppression of the mTOR pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1361-4

A systems biology investigation of neurodegenerative dementia reveals a pivotal role of autophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1361-4

Autophagy is disrupted in a knock-in mouse model of juvenile neuronal ceroid lipofuscinosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1361-4

Autophagy and ageing: implications for age-related neurodegenerative diseases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1361-4

Trehalose delays the progression of amyotrophic lateral sclerosis by enhancing autophagy in motoneurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1361-4

Unravelling mitochondrial pathways to Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1361-4

mTOR dysfunction contributes to vacuolar pathology and weakness in valosin-containing protein associated inclusion body myopathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1361-4

Involvement of members of the Rab family and related small GTPases in autophagosome formation and maturation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1361-4

Rapamycin delays disease onset and prevents PrP plaque deposition in a mouse model of Gerstmann-Sträussler-Scheinker disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1361-4

Loss of autophagy in pro-opiomelanocortin neurons perturbs axon growth and causes metabolic dysregulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1361-4

Mutations in CHMP2B in lower motor neuron predominant amyotrophic lateral sclerosis (ALS).

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1361-4

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1361-4

A population of rat liver lysosomes responsible for the selective uptake and degradation of cytosolic proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1361-4

Impaired degradation of mutant alpha-synuclein by chaperone-mediated autophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1361-4

Chaperone-mediated autophagy: roles in disease and aging

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1361-4

Acid β-glucosidase mutants linked to Gaucher disease, Parkinson disease, and Lewy body dementia alter α-synuclein processing.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1361-4

Macroautophagy is defective in mucolipin-1-deficient mouse neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1361-4

HDAC6 at the Intersection of Neuroprotection and Neurodegeneration.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1361-4

Loss of P-type ATPase ATP13A2/PARK9 function induces general lysosomal deficiency and leads to Parkinson disease neurodegeneration.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1361-4

Mutations in UBQLN2 cause dominant X-linked juvenile and adult-onset ALS and ALS/dementia

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1361-4

Identification of autophagosome-associated proteins and regulators by quantitative proteomic analysis and genetic screens.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1361-4

Neuronal Tsc1/2 complex controls autophagy through AMPK-dependent regulation of ULK1

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1361-4

Chaperone-Mediated Autophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1361-4

Hypoxic stress activates chaperone-mediated autophagy and modulates neuronal cell survival.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1361-4

Autophagy and viruses: adversaries or allies?

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1361-4

Mitochondrial quality control in neurodegenerative diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1361-4

Tubulin polymerization-promoting protein (TPPP/p25α) promotes unconventional secretion of α-synuclein through exophagy by impairing autophagosome-lysosome fusion

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1361-4

Maturation of autophagic vacuoles in Mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1361-4

Role of LAMP-2 in lysosome biogenesis and autophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1361-4

Seeing is believing: the impact of electron microscopy on autophagy research

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1361-4

Autophagy: a lysosomal degradation pathway with a central role in health and disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1361-4

UBQLN2/P62 cellular recycling pathways in amyotrophic lateral sclerosis and frontotemporal dementia

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1361-4

Neuronal loss and brain atrophy in mice lacking cathepsins B and L

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1361-4

The machinery of macroautophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1361-4

Functional multivesicular bodies are required for autophagic clearance of protein aggregates associated with neurodegenerative disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1361-4

Lithium delays progression of amyotrophic lateral sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1361-4

Autophagy and amyotrophic lateral sclerosis: The multiple roles of lithium

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1361-4

ER stress inhibits neuronal death by promoting autophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1361-4

Lysosomal fusion and SNARE function are impaired by cholesterol accumulation in lysosomal storage disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1361-4

Disrupted autophagy leads to dopaminergic axon and dendrite degeneration and promotes presynaptic accumulation of α-synuclein and LRRK2 in the brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1361-4

LC3 binding to the scaffolding protein JIP1 regulates processive dynein-driven transport of autophagosomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1361-4

The Atg16L complex specifies the site of LC3 lipidation for membrane biogenesis in autophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1361-4

Dysfunction of endocytic and autophagic pathways in a lysosomal storage disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1361-4

The E3-ubiquitin ligase TRIM50 interacts with HDAC6 and p62, and promotes the sequestration and clearance of ubiquitinated proteins into the aggresome

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1361-4

p62 accumulates and enhances aggregate formation in model systems of familial amyotrophic lateral sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1361-4

Sequestosome 1/p62 links familial ALS mutant SOD1 to LC3 via an ubiquitin-independent mechanism.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1361-4

Insulin activation of Rheb, a mediator of mTOR/S6K/4E-BP signaling, is inhibited by TSC1 and 2

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1361-4

The protein-vesicle network of autophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1361-4

VCP mutations causing frontotemporal lobar degeneration disrupt localization of TDP-43 and induce cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1361-4

ER exit sites are physical and functional core autophagosome biogenesis components

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1361-4

AP1 is essential for generation of autophagosomes from the trans-Golgi network.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1361-4

Rab7 is required for the normal progression of the autophagic pathway in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1361-4

Loss of ALS2/Alsin exacerbates motor dysfunction in a SOD1-expressing mouse ALS model by disturbing endolysosomal trafficking

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1361-4

Mitochondria supply membranes for autophagosome biogenesis during starvation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1361-4

Autophagy: regulation and role in development

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1361-4

Autophagosomes form at ER-mitochondria contact sites

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1361-4

Suppression of basal autophagy in neural cells causes neurodegenerative disease in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1361-4

A subdomain of the endoplasmic reticulum forms a cradle for autophagosome formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1361-4

Exercise induces autophagy in peripheral tissues and in the brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1361-4

Autophagy in ageing and ageing-associated diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1361-4

Lithium induces clearance of protease resistant prion protein in prion-infected cells by induction of autophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1361-4

Regulation of presynaptic neurotransmission by macroautophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1361-4

Products of endocytosis and autophagy are retrieved from axons by regulated retrograde organelle transport

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1361-4

Metabolism and mis-metabolism of the neuropathological signature protein TDP-43.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1361-4

Rheb GTPase is a direct target of TSC2 GAP activity and regulates mTOR signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1361-4

Characterization of autophagosome formation site by a hierarchical analysis of mammalian Atg proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1361-4

HDAC6 and microtubules are required for autophagic degradation of aggregated huntingtin

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1361-4

Subversion of cellular autophagosomal machinery by RNA viruses

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1361-4

Role for Rab7 in maturation of late autophagic vacuoles

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1361-4

Autophagy induced by the class III histone deacetylase Sirt1 prevents prion peptide neurotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1361-4

Neuroprotective role of Sirt1 in mammalian models of Huntington's disease through activation of multiple Sirt1 targets

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1361-4

Transcriptional regulation by Pho23 modulates the frequency of autophagosome formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1361-4

Exome sequencing reveals VCP mutations as a cause of familial ALS

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1361-4

Valosin-containing protein (VCP) is required for autophagy and is disrupted in VCP disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1361-4

ULK-Atg13-FIP200 complexes mediate mTOR signaling to the autophagy machinery

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1361-4

LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processing

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1361-4

Aberrant interaction between Parkinson disease-associated mutant UCH-L1 and the lysosomal receptor for chaperone-mediated autophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1361-4

Degradation of Amyotrophic Lateral Sclerosis-linked Mutant Cu,Zn-Superoxide Dismutase Proteins by Macroautophagy and the Proteasome

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1361-4

Dynein- and activity-dependent retrograde transport of autophagosomes in neuronal axons

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1361-4

Chaperone-mediated autophagy: a unique way to enter the lysosome world

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1361-4

Constitutive activation of chaperone-mediated autophagy in cells with impaired macroautophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1361-4

Activation of chaperone-mediated autophagy during oxidative stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1361-4

Altered dynamics of the lysosomal receptor for chaperone-mediated autophagy with age.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1361-4

AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1361-4

Fighting disease by selective autophagy of aggregate-prone proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1361-4

Mechanisms of acute axonal degeneration in the optic nerve in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1361-4

Lysosomal dysfunction causes neurodegeneration in mucolipidosis II 'knock-in' mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1361-4

Loss of autophagy in the central nervous system causes neurodegeneration in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1361-4

Essential role for autophagy protein Atg7 in the maintenance of axonal homeostasis and the prevention of axonal degeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1361-4

DAP1, a novel substrate of mTOR, negatively regulates autophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1361-4

Route to destruction: autophagosomes SNARE lysosomes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1361-4

Autophagic failure promotes the exocytosis and intercellular transfer of α-synuclein.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1361-4

ESCRT-III dysfunction causes autophagosome accumulation and neurodegeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1361-4

HDAC6 controls autophagosome maturation essential for ubiquitin-selective quality-control autophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1361-4

Disease-causing mutations in parkin impair mitochondrial ubiquitination, aggregation, and HDAC6-dependent mitophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1361-4

Neuronal autophagy and neurodevelopmental disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1361-4

Lysosomal proteolysis inhibition selectively disrupts axonal transport of degradative organelles and causes an Alzheimer's-like axonal dystrophy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1361-4

Neural-specific deletion of FIP200 leads to cerebellar degeneration caused by increased neuronal death and axon degeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1361-4

Cholesterol accumulation is associated with lysosomal dysfunction and autophagic stress in Npc1 -/- mouse brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1361-4

Neuronal cell death in transmissible spongiform encephalopathies (prion diseases) revisited: from apoptosis to autophagy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1361-4

Genome-wide analysis reveals mechanisms modulating autophagy in normal brain aging and in Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1361-4

Mitochondrial outer-membrane protein FUNDC1 mediates hypoxia-induced mitophagy in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1361-4

Rheb binding to mammalian target of rapamycin (mTOR) is regulated by amino acid sufficiency

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1361-4

TBC1D14 regulates autophagosome formation via Rab11- and ULK1-positive recycling endosomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1361-4

REST and stress resistance in ageing and Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1361-4

Acetylation targets the M2 isoform of pyruvate kinase for degradation through chaperone-mediated autophagy and promotes tumor growth.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1361-4

Autophagosomes initiate distally and mature during transport toward the cell soma in primary neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1361-4

Autophagy sequesters damaged lysosomes to control lysosomal biogenesis and kidney injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1361-4

Genetic and chemical correction of cholesterol accumulation and impaired autophagy in hepatic and neural cells derived from Niemann-Pick Type C patient-specific iPS cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1361-4

Dysfunction of the autophagy/lysosomal degradation pathway is a shared feature of the genetic synucleinopathies

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1361-4

MTORC1 functions as a transcriptional regulator of autophagy by preventing nuclear transport of TFEB.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1361-4

The nutrient-responsive transcription factor TFE3 promotes autophagy, lysosomal biogenesis, and clearance of cellular debris

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1361-4

Rag GTPases mediate amino acid-dependent recruitment of TFEB and MITF to lysosomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1361-4

RRAG GTPases link nutrient availability to gene expression, autophagy and lysosomal biogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1361-4

Consequences of the selective blockage of chaperone-mediated autophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1361-4

Autophagy requires endoplasmic reticulum targeting of the PI3-kinase complex via Atg14L.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1361-4

Hypoxia-induced autophagy: cell death or cell survival?

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1361-4

Transcriptional activation of lysosomal exocytosis promotes cellular clearance

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1361-4

Rheb regulates mitophagy induced by mitochondrial energetic status

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1361-4

Emerging functions of the VCP/p97 AAA-ATPase in the ubiquitin system

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1361-4

Lysosomal membrane permeability stimulates protein aggregate formation in neurons of a lysosomal disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1361-4

Protein turnover via autophagy: implications for metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1361-4

In vivo analysis of autophagy in response to nutrient starvation using transgenic mice expressing a fluorescent autophagosome marker

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1361-4

The phytoestrogen genistein modulates lysosomal metabolism and transcription factor EB (TFEB) activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1361-4

Characteristics and requirements of basal autophagy in HEK 293 cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1361-4

FK506 reduces abnormal prion protein through the activation of autolysosomal degradation and prolongs survival in prion-infected mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1361-4

Parkin is recruited selectively to impaired mitochondria and promotes their autophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1361-4

Pathogenic role of BECN1/Beclin 1 in the development of amyotrophic lateral sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1361-4

mTOR inhibits autophagy by controlling ULK1 ubiquitylation, self-association and function through AMBRA1 and TRAF6.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1361-4

Endoplasmic reticulum stress activates autophagy but not the proteasome in neuronal cells: implications for Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1361-4

Primary LAMP-2 deficiency causes X-linked vacuolar cardiomyopathy and myopathy (Danon disease).

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1361-4

Extensive involvement of autophagy in Alzheimer disease: an immuno-electron microscopy study.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1361-4

Nix is a selective autophagy receptor for mitochondrial clearance

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1361-4

Autophagy is activated for cell survival after endoplasmic reticulum stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1361-4

Parkin-mediated K63-linked polyubiquitination: a signal for targeting misfolded proteins to the aggresome-autophagy pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1361-4

Parkin-mediated K63-linked polyubiquitination targets misfolded DJ-1 to aggresomes via binding to HDAC6

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1361-4

Chaperone-mediated autophagy: molecular mechanisms and physiological relevance

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1361-4

Interplay of LRRK2 with chaperone-mediated autophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1361-4

HSV-1 ICP34.5 confers neurovirulence by targeting the Beclin 1 autophagy protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1361-4

Autophagy protects against Sindbis virus infection of the central nervous system

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1361-4

Tsc1 (hamartin) confers neuroprotection against ischemia by inducing autophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1361-4

Early steps in autophagy depend on direct phosphorylation of Atg9 by the Atg1 kinase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1361-4

ALS phenotypes with mutations in CHMP2B (charged multivesicular body protein 2B)

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1361-4

An overview of autophagy: morphology, mechanism, and regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1361-4

The cell biology of disease: lysosomal storage disorders: the cellular impact of lysosomal dysfunction

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1361-4

Mutation in the alpha-synuclein gene identified in families with Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1361-4

21 January 2018

Prion Protein Biology

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1361-4

Role of hypothalamic proopiomelanocortin neuron autophagy in the control of appetite and leptin response

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1361-4

Phosphorylation-regulated degradation of the tumor-suppressor form of PED by chaperone-mediated autophagy in lung cancer cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1361-4

VMA21 deficiency prevents vacuolar ATPase assembly and causes autophagic vacuolar myopathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1361-4

Plasma membrane contributes to the formation of pre-autophagosomal structures

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1361-4

Mitophagy mechanisms and role in human diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1361-4

How positive-strand RNA viruses benefit from autophagosome maturation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1361-4

Inclusion body formation, macroautophagy, and the role of HDAC6 in neurodegeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1361-4

Hexokinase-II positively regulates glucose starvation-induced autophagy through TORC1 inhibition

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1361-4

The transcription factor TFEB links mTORC1 signaling to transcriptional control of lysosome homeostasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1361-4

Axonal damage, autophagy and neuronal survival

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1361-4

Autophagy promotes survival of retinal ganglion cells after optic nerve axotomy in mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1361-4

Inhibitory effect of dietary lipids on chaperone-mediated autophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1361-4

Interactions between autophagy receptors and ubiquitin-like proteins form the molecular basis for selective autophagy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1361-4

Analysis of optineurin in frontotemporal lobar degeneration.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1361-4

Ubiquilin functions in autophagy and is degraded by chaperone-mediated autophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1361-4

SQSTM1 mutations in frontotemporal lobar degeneration and amyotrophic lateral sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1361-4

Protein kinase Ctheta is required for autophagy in response to stress in the endoplasmic reticulum

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1361-4

Augmenting CNS glucocerebrosidase activity as a therapeutic strategy for parkinsonism and other Gaucher-related synucleinopathies

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1361-4

Reactive oxygen species are essential for autophagy and specifically regulate the activity of Atg4

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1361-4

Substrate recognition in selective autophagy and the ubiquitin-proteasome system.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1361-4

Differential roles of the ubiquitin proteasome system and autophagy in the clearance of soluble and aggregated TDP-43 species

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1361-4

Sequestosome 1/p62 is a polyubiquitin chain binding protein involved in ubiquitin proteasome degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1361-4

Expression of Ambra1 in mouse brain during physiological and Alzheimer type aging.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1361-4

A lysosome-to-nucleus signalling mechanism senses and regulates the lysosome via mTOR and TFEB

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1361-4

Excessive autophagy contributes to neuron death in cerebral ischemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1361-4

A current perspective of autophagosome biogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1361-4

Autophagy is a part of ultrastructural synaptic pathology in Creutzfeldt-Jakob disease: a brain biopsy study

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1361-4

Alfy, a novel FYVE-domain-containing protein associated with protein granules and autophagic membranes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1361-4

Mutations in the endosomal ESCRTIII-complex subunit CHMP2B in frontotemporal dementia

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1361-4

2-Hydroxypropyl-β-cyclodextrin promotes transcription factor EB-mediated activation of autophagy: implications for therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1361-4

Transcription factor EB (TFEB) is a new therapeutic target for Pompe disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1361-4

Beclin 1 gene transfer activates autophagy and ameliorates the neurodegenerative pathology in alpha-synuclein models of Parkinson's and Lewy body diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1361-4

Alpha-synuclein in Lewy bodies

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1361-4

The beginning of the end: how scaffolds nucleate autophagosome biogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1361-4

Neuronal pigmented autophagic vacuoles: lipofuscin, neuromelanin, and ceroid as macroautophagic responses during aging and disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1361-4

Bif-1 regulates Atg9 trafficking by mediating the fission of Golgi membranes during autophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1361-4

The EM structure of the TRAPPIII complex leads to the identification of a requirement for COPII vesicles on the macroautophagy pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1361-4

Lysine 63-linked ubiquitination promotes the formation and autophagic clearance of protein inclusions associated with neurodegenerative diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1361-4

Parkin-mediated selective mitochondrial autophagy, mitophagy: Parkin purges damaged organelles from the vital mitochondrial network

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1361-4

Accumulation of autophagic vacuoles and cardiomyopathy in LAMP-2-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1361-4

p62/sequestosome 1 binds to TDP-43 in brains with frontotemporal lobar degeneration with TDP-43 inclusions

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1361-4

Quality control of mitochondria: protection against neurodegeneration and ageing

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1361-4

Disruption of the autophagy-lysosome pathway is involved in neuropathology of the nclf mouse model of neuronal ceroid lipofuscinosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1361-4

RNA dysfunction and aggrephagy at the centre of an amyotrophic lateral sclerosis/frontotemporal dementia disease continuum

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1361-4

Macroautophagy can press a brake on presynaptic neurotransmission

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1361-4

Structure and Function of Parkin, PINK1, and DJ-1, the Three Musketeers of Neuroprotection

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1361-4

VCP/p97 is essential for maturation of ubiquitin-containing autophagosomes and this function is impaired by mutations that cause IBMPFD

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1361-4

A cluster of thin tubular structures mediates transformation of the endoplasmic reticulum to autophagic isolation membrane

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1361-4

Mitophagy and neurodegeneration: the zebrafish model system

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1361-4

Secondary lipid accumulation in lysosomal disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1361-4

Exit from the Golgi is required for the expansion of the autophagosomal phagophore in yeast Saccharomyces cerevisiae

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1361-4

Parkin interacts with Ambra1 to induce mitophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1361-4

Autophagy activators rescue and alleviate pathogenesis of a mouse model with proteinopathies of the TAR DNA-binding protein 43

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1361-4

Induction of autophagy in axonal dystrophy and degeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1361-4

Tau fragmentation, aggregation and clearance: the dual role of lysosomal processing

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1361-4

Atg5 and Ambra1 differentially modulate neurogenesis in neural stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1361-4

A double-edged sword with therapeutic potential: an updated role of autophagy in ischemic cerebral injury.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1361-4

Chaperone-mediated autophagy is defective in mucolipidosis type IV.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1361-4

Autophagic dysfunction in mucolipidosis type IV patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1361-4

Phosphorylation of the autophagy receptor optineurin restricts Salmonella growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1361-4

α-Synuclein impairs macroautophagy: implications for Parkinson's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1361-4

Wild type alpha-synuclein is degraded by chaperone-mediated autophagy and macroautophagy in neuronal cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1361-4

Autophagy gone awry in neurodegenerative diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1361-4

Abberant alpha-synuclein confers toxicity to neurons in part through inhibition of chaperone-mediated autophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1361-4

Neuronal autophagy in cerebral ischemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1361-4

Regulation of neuronal survival factor MEF2D by chaperone-mediated autophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1361-4

Autophagy in axonal and dendritic degeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1361-4

Microtubule and kinesin/dynein-dependent, bi-directional transport of autolysosomes in neurites of PC12 cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1361-4

3D tomography reveals connections between the phagophore and endoplasmic reticulum

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1361-4

A neuron-specific role for autophagy in antiviral defense against herpes simplex virus

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1361-4

Autophagy in the control and pathogenesis of viral infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1361-4

Autophagy and selective deployment of Atg proteins in antiviral defense

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1361-4

Starvation and ULK1-dependent cycling of mammalian Atg9 between the TGN and endosomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1361-4

Termination of autophagy and reformation of lysosomes regulated by mTOR

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1361-4

Regulation of neuronal autophagy in axon: implication of autophagy in axonal function and dysfunction/degeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1361-4

The tyrosine kinase inhibitor imatinib mesylate delays prion neuroinvasion by inhibiting prion propagation in the periphery.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1361-4

Restoration of chaperone-mediated autophagy in aging liver improves cellular maintenance and hepatic function

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1361-4

Oxidative stress induces parallel autophagy and mitochondria dysfunction in human glioma U251 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1361-4

Rapamycin treatment augments motor neuron degeneration in SOD1(G93A) mouse model of amyotrophic lateral sclerosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1361-4

Cerebral ischemia-reperfusion-induced autophagy protects against neuronal injury by mitochondrial clearance

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1361-4

Optineurin negatively regulates TNFalpha- induced NF-kappaB activation by competing with NEMO for ubiquitinated RIP

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1361-4

After the banquet: mitochondrial biogenesis, mitophagy, and cell survival

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1361-4

mTORC1 senses lysosomal amino acids through an inside-out mechanism that requires the vacuolar H(+)-ATPase

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1361-4

Induction of autophagy by amino-acid deprivation in perfused rat liver

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1361-4

10.1007/S00401-014-1361-4

21 January 2018

Identifiers

DOI

1 reference

PubMed ID

25367385

Dimensions Publication ID

1 September 2017

0 references

1 reference

PubMed ID

25367385