(Q37958101)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22098618%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

title

Cross-functional E3 ligases Parkin and C-terminus Hsp70-interacting protein in neurodegenerative disorders (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22098618%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

1 reference

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22098618%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

author name string

Kaveri Pradhan

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22098618%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

R Karunya

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22098618%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

Rashmi K Ambasta

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22098618%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

Henry W Querfurth

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22098618%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

language of work or name

English

0 references

publication date

21 December 2011

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22098618%20AND%20SRC:MED&resulttype=core&format=json

Journal of Neurochemistry

17 January 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22098618%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

volume

120

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22098618%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

page(s)

350-370

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22098618%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

issue

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22098618%20AND%20SRC:MED&resulttype=core&format=json

Cdh1/Hct1-APC is essential for the survival of postmitotic neurons.

17 January 2020

cites work

1 reference

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CHIP protects from the neurotoxicity of expanded and wild-type ataxin-1 and promotes their ubiquitination and degradation

21 January 2018

1 reference

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Features of the parkin/ariadne-like ubiquitin ligase, HHARI, that regulate its interaction with the ubiquitin-conjugating enzyme, Ubch7

21 January 2018

1 reference

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Inhibition of proteasomal activity causes inclusion formation in neuronal and non-neuronal cells overexpressing Parkin

21 January 2018

1 reference

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Sequestosome 1/p62 shuttles polyubiquitinated tau for proteasomal degradation

21 January 2018

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Tau-mediated neurodegeneration in Alzheimer's disease and related disorders

21 January 2018

1 reference

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Identification of CHIP, a novel tetratricopeptide repeat-containing protein that interacts with heat shock proteins and negatively regulates chaperone functions

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07588.X

Antisense targeting of E6AP elevates p53 in HPV-infected cells but not in normal cells

21 January 2018

1 reference

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Hydrogen peroxide mediates amyloid beta protein toxicity

21 January 2018

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Global changes to the ubiquitin system in Huntington's disease.

21 January 2018

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Parkin is transcriptionally regulated by ATF4: evidence for an interconnection between mitochondrial stress and ER stress

21 January 2018

1 reference

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Comparative analysis of genetic modifiers in Drosophila points to common and distinct mechanisms of pathogenesis among polyglutamine diseases

21 January 2018

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The interplay between PolyQ and protein context delays aggregation by forming a reservoir of protofibrils

21 January 2018

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In vivo amyloid imaging in autopsy-confirmed Parkinson disease with dementia

21 January 2018

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The molecular links between TDP-43 dysfunction and neurodegeneration

21 January 2018

1 reference

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Parkin promotes intracellular Abeta1-42 clearance

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07588.X

Parkin gene therapy could treat Parkinson's disease.

21 January 2018

1 reference

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Variation in RTN3 and PPIL2 genes does not influence platelet membrane beta-secretase activity or susceptibility to alzheimer's disease in the northern Irish population

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07588.X

Increased Abeta1-42 production sensitizes neuroblastoma cells for ER stress toxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07588.X

Broad activation of the ubiquitin-proteasome system by Parkin is critical for mitophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07588.X

Ubiquitin immunoreactivity of multiple polypeptides in rat brain synaptic membranes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07588.X

Multiple ubiquitin conjugates are present in rat brain synaptic membranes and postsynaptic densities.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07588.X

Functional alterations of the ubiquitin-proteasome system in motor neurons of a mouse model of familial amyotrophic lateral sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07588.X

Parkin-mediated ubiquitin signalling in aggresome formation and autophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07588.X

Co-chaperone CHIP associates with mutant Cu/Zn-superoxide dismutase proteins linked to familial amyotrophic lateral sclerosis and promotes their degradation by proteasomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07588.X

Co-chaperone CHIP promotes aggregation of ataxin-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07588.X

Parkin and Hsp70 sacked by BAG5.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07588.X

Parkin ubiquitinates the alpha-synuclein-interacting protein, synphilin-1: implications for Lewy-body formation in Parkinson disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07588.X

S-nitrosylation of parkin regulates ubiquitination and compromises parkin's protective function

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07588.X

The ubiquitin-proteasome pathway: on protein death and cell life

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07588.X

The ubiquitin proteasome system in neurodegenerative diseases: sometimes the chicken, sometimes the egg.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07588.X

From Charcot to Lou Gehrig: deciphering selective motor neuron death in ALS

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07588.X

Ubiquitination regulates PSD-95 degradation and AMPA receptor surface expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07588.X

The co-chaperone CHIP regulates protein triage decisions mediated by heat-shock proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07588.X

Parkinson's disease: insights from pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07588.X

Transcriptional repression of p53 by parkin and impairment by mutations associated with autosomal recessive juvenile Parkinson's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07588.X

CHIP activates HSF1 and confers protection against apoptosis and cellular stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07588.X

Regulation of the cytoplasmic quality control protein degradation pathway by BAG2

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07588.X

Parkin prevents mitochondrial swelling and cytochrome c release in mitochondria-dependent cell death.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07588.X

Molecular Pathways of Neurodegeneration in Parkinson's Disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07588.X

SCF and Cullin/Ring H2-based ubiquitin ligases

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07588.X

Proteasomal degradation of mutant superoxide dismutases linked to amyotrophic lateral sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07588.X

Deletion of the ubiquitin ligase CHIP leads to the accumulation, but not the aggregation, of both endogenous phospho- and caspase-3-cleaved tau species.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07588.X

The high-affinity HSP90-CHIP complex recognizes and selectively degrades phosphorylated tau client proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07588.X

Brain CHIP: removing the culprits in neurodegenerative disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07588.X

Akt and CHIP coregulate tau degradation through coordinated interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07588.X

Proteasome inhibition in oxidative stress neurotoxicity: implications for heat shock proteins.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07588.X

Chaperones increase association of tau protein with microtubules

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07588.X

Concurrence of alpha-synuclein and tau brain pathology in the Contursi kindred

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07588.X

The Machado-Joseph disease-associated mutant form of ataxin-3 regulates parkin ubiquitination and stability

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07588.X

A genome wide analysis of ubiquitin ligases in APP processing identifies a novel regulator of BACE1 mRNA levels

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07588.X

Intracellularly generated amyloid-beta peptide counteracts the antiapoptotic function of its precursor protein and primes proapoptotic pathways for activation by other insults in neuroblastoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07588.X

The chaperone-associated ubiquitin ligase CHIP is able to target p53 for proteasomal degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07588.X

FTD and ALS: a tale of two diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07588.X

A sporadic Parkinson disease model via silencing of the ubiquitin-proteasome/E3 ligase component SKP1A

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07588.X

Modulating apoptosis as a target for effective therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07588.X

Brain proteasomal function in sporadic Parkinson's disease and related disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07588.X

Sensory-motor deficits and neurofilament disorganization in gigaxonin-null mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07588.X

Diseases of unstable repeat expansion: mechanisms and common principles

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07588.X

Lithium inhibits Abeta-induced stress in endoplasmic reticulum of rabbit hippocampus but does not prevent oxidative damage and tau phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07588.X

The ubiquitin-proteasome proteolytic pathway: destruction for the sake of construction

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07588.X

Mutant huntingtin-impaired degradation of beta-catenin causes neurotoxicity in Huntington's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07588.X

Alpha-synuclein and neurodegenerative diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07588.X

Parkin-deficient mice exhibit nigrostriatal deficits but not loss of dopaminergic neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07588.X

Imaging amyloid deposition in Lewy body diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07588.X

SCFFbx2-E3-ligase-mediated degradation of BACE1 attenuates Alzheimer's disease amyloidosis and improves synaptic function

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07588.X

21 January 2018

CHIP-ping away at tau.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07588.X

Formation of neurofibrillary tangles in P301l tau transgenic mice induced by Abeta 42 fibrils

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07588.X

Mitochondrial pathology and apoptotic muscle degeneration in Drosophila parkin mutants

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07588.X

Genetic and genomic studies of Drosophila parkin mutants implicate oxidative stress and innate immune responses in pathogenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07588.X

Soluble protein oligomers in neurodegeneration: lessons from the Alzheimer's amyloid beta-peptide

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07588.X

U box proteins as a new family of ubiquitin-protein ligases

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07588.X

U-box protein carboxyl terminus of Hsc70-interacting protein (CHIP) mediates poly-ubiquitylation preferentially on four-repeat Tau and is involved in neurodegeneration of tauopathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07588.X

Ubiquitin-proteasome-mediated local protein degradation and synaptic plasticity

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07588.X

Role of ubiquitin-proteasome-mediated proteolysis in nervous system disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07588.X

Targeting amyloid precursor protein.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07588.X

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07588.X

Basic Medical Research Award. The ubiquitin system.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07588.X

Endoplasmic reticulum chaperones inhibit the production of amyloid-beta peptides.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07588.X

AMPAR removal underlies Abeta-induced synaptic depression and dendritic spine loss

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07588.X

C-terminus of heat shock protein 70-interacting protein facilitates degradation of apoptosis signal-regulating kinase 1 and inhibits apoptosis signal-regulating kinase 1-dependent apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07588.X

Effect of wild-type or mutant Parkin on oxidative damage, nitric oxide, antioxidant defenses, and the proteasome

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07588.X

Proteasomal inhibition causes the formation of protein aggregates containing a wide range of proteins, including nitrated proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07588.X

Modifications of p53 and the DNA damage response in cells expressing mutant form of the protein huntingtin

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07588.X

Parkin suppresses unfolded protein stress-induced cell death through its E3 ubiquitin-protein ligase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07588.X

An unfolded putative transmembrane polypeptide, which can lead to endoplasmic reticulum stress, is a substrate of Parkin

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07588.X

CHIP is associated with Parkin, a gene responsible for familial Parkinson's disease, and enhances its ubiquitin ligase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07588.X

Huntington's disease: from pathology and genetics to potential therapies

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07588.X

Physical and functional interaction between Dorfin and Valosin-containing protein that are colocalized in ubiquitylated inclusions in neurodegenerative disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07588.X

Amyloid-β and tau--a toxic pas de deux in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07588.X

The lore of the RINGs: substrate recognition and catalysis by ubiquitin ligases

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07588.X

Co-chaperone CHIP associates with expanded polyglutamine protein and promotes their degradation by proteasomes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07588.X

The role of mutant TAR DNA-binding protein 43 in amyotrophic lateral sclerosis and frontotemporal lobar degeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07588.X

CHIP is a U-box-dependent E3 ubiquitin ligase: identification of Hsc70 as a target for ubiquitylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07588.X

RING finger proteins: mediators of ubiquitin ligase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07588.X

Amyotrophic lateral sclerosis. unfolding the toxicity of the misfolded

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07588.X

Amyloid beta induces neuronal cell death through ROS-mediated ASK1 activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07588.X

Overexpression of the cochaperone CHIP enhances Hsp70-dependent folding activity in mammalian cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07588.X

Enhanced accumulation of phosphorylated alpha-synuclein and elevated beta-amyloid 42/40 ratio caused by expression of the presenilin-1 deltaT440 mutant associated with familial Lewy body disease and variant Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07588.X

Loss of HRD1-mediated protein degradation causes amyloid precursor protein accumulation and amyloid-beta generation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07588.X

Identification, expression, and chromosomal localization of ubiquitin conjugating enzyme 7 (UBE2G2), a human homologue of the Saccharomyces cerevisiae ubc7 gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07588.X

Amyloid beta-peptide effects on synaptosomes from apolipoprotein E-deficient mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07588.X

The Relationship between Parkin and Protein Aggregation in Neurodegenerative Diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07588.X

Parkin mediates beclin-dependent autophagic clearance of defective mitochondria and ubiquitinated Abeta in AD models

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07588.X

Amyotrophic lateral sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07588.X

Expression of human amyloid precursor protein in the skeletal muscles of Drosophila results in age- and activity-dependent muscle weakness

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07588.X

cDNA cloning, characterization, and chromosome mapping of UBE2E2 encoding a human ubiquitin-conjugating E2 enzyme

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07588.X

Parkinson's disease: viral vector delivery of parkin generates model results in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07588.X

Mutations in the parkin gene cause autosomal recessive juvenile parkinsonism

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07588.X

Parkinson disease, 10 years after its genetic revolution: multiple clues to a complex disorder

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07588.X

Parkin is protective for substantia nigra dopamine neurons in a tau gene transfer neurodegeneration model

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07588.X

Phosphorylation by the c-Abl protein tyrosine kinase inhibits parkin's ubiquitination and protective function

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07588.X

A novel ubiquitination factor, E4, is involved in multiubiquitin chain assembly.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07588.X

Phosphorylated tau and the neurodegenerative foldopathies

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07588.X

Lewy Body Pathology in Alzheimer's Disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07588.X

CHIP and HSPs interact with beta-APP in a proteasome-dependent manner and influence Abeta metabolism.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07588.X

Parkin enhances mitochondrial biogenesis in proliferating cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07588.X

TDP-43 and FUS/TLS: emerging roles in RNA processing and neurodegeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07588.X

Astrocytic but not neuronal increased expression and redistribution of parkin during unfolded protein stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07588.X

Ubiquitination of alpha-synuclein by Siah-1 promotes alpha-synuclein aggregation and apoptotic cell death.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07588.X

Enhanced proteolysis of beta-amyloid in APP transgenic mice prevents plaque formation, secondary pathology, and premature death.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07588.X

Multiple pathways contribute to the pathogenesis of Huntington disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07588.X

Proteasomal dysfunction in aging and Huntington disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07588.X

SEL-10 interacts with presenilin 1, facilitates its ubiquitination, and alters A-beta peptide production

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07588.X

RNA toxicity is a component of ataxin-3 degeneration in Drosophila

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07588.X

Ubiquitin-proteasome system dysfunction in Parkinson's disease: current evidence and controversies

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07588.X

A novel brain-enriched E3 ubiquitin ligase RNF182 is up regulated in the brains of Alzheimer's patients and targets ATP6V0C for degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07588.X

Lentiviral vector delivery of parkin prevents dopaminergic degeneration in an alpha-synuclein rat model of Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07588.X

Relationship between beta-amyloid degradation and the 26S proteasome in neural cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07588.X

Association between early-onset Parkinson's disease and mutations in the parkin gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07588.X

Roles of heat-shock protein 90 in maintaining and facilitating the neurodegenerative phenotype in tauopathies

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07588.X

Cdk5 phosphorylates Cdh1 and modulates cyclin B1 stability in excitotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07588.X

Impaired mitochondrial dynamics and abnormal interaction of amyloid beta with mitochondrial protein Drp1 in neurons from patients with Alzheimer's disease: implications for neuronal damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07588.X

rAAV-mediated nigral human parkin over-expression partially ameliorates motor deficits via enhanced dopamine neurotransmission in a rat model of Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07588.X

Progressive Purkinje cell degeneration in tambaleante mutant mice is a consequence of a missense mutation in HERC1 E3 ubiquitin ligase

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07588.X

Does impairment of the ubiquitin-proteasome system or the autophagy-lysosome pathway predispose individuals to neurodegenerative disorders such as Parkinson's disease?

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07588.X

CHIP: a link between the chaperone and proteasome systems

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07588.X

Failure of the ubiquitin-proteasome system in Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07588.X

The Hsc70 co-chaperone CHIP targets immature CFTR for proteasomal degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07588.X

Alterations of Hrd1 expression in various encephalic regional neurons in 6-OHDA model of Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07588.X

Suppression of Parkin enhances nigrostriatal and motor neuron lesion in mice over-expressing human-mutated tau protein.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07588.X

CHIP suppresses polyglutamine aggregation and toxicity in vitro and in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07588.X

Parkin: a multifaceted ubiquitin ligase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07588.X

Molecular pathophysiology of Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07588.X

Parkin mediates the degradation-independent ubiquitination of Hsp70

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07588.X

CHIP deletion reveals functional redundancy of E3 ligases in promoting degradation of both signaling proteins and expanded glutamine proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07588.X

Parkin attenuates wild-type tau modification in the presence of beta-amyloid and alpha-synuclein

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07588.X

Modulation of neurodegeneration by molecular chaperones

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07588.X

CHIP is a chaperone-dependent E3 ligase that ubiquitylates unfolded protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07588.X

CHIP: a quality-control E3 ligase collaborating with molecular chaperones

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07588.X

Molecular mechanisms of proteasome assembly

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07588.X

p53 mediates nontranscriptional cell death in dopaminergic cells in response to proteasome inhibition

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07588.X

S-nitrosylation of Drp1 links excessive mitochondrial fission to neuronal injury in neurodegeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07588.X

Dorfin ubiquitylates mutant SOD1 and prevents mutant SOD1-mediated neurotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07588.X

21 January 2018

Huntington's disease.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07588.X

Blocking Abeta42 accumulation delays the onset and progression of tau pathology via the C terminus of heat shock protein70-interacting protein: a mechanistic link between Abeta and tau pathology.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07588.X

Amyloid-like aggregates sequester numerous metastable proteins with essential cellular functions

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07588.X

Reversing neurodegeneration: a promise unfolds

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07588.X

Mitochondrial dysfunction and oxidative damage in parkin-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07588.X

HDAC6 rescues neurodegeneration and provides an essential link between autophagy and the UPS

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07588.X

Loss of MARCH5 mitochondrial E3 ubiquitin ligase induces cellular senescence through dynamin-related protein 1 and mitofusin 1

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07588.X

Paired helical filaments from Alzheimer disease patients contain cytoskeletal components

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07588.X

Ubiquitin is detected in neurofibrillary tangles and senile plaque neurites of Alzheimer disease brains

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07588.X

The effects of parkin suppression on the behaviour, amyloid processing, and cell survival in APP mutant transgenic mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07588.X

Parkin protects against the toxicity associated with mutant alpha-synuclein: proteasome dysfunction selectively affects catecholaminergic neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07588.X

CHIP and Hsp70 regulate tau ubiquitination, degradation and aggregation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07588.X

Unraveling the complexity of amyotrophic lateral sclerosis: recent advances from the transgenic mutant SOD1 mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07588.X

Proteasomes and their kin: proteases in the machine age

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07588.X

The inositol phosphatase MTMR4 is a novel target of the ubiquitin ligase Nedd4

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07588.X

GSK3 and p53 - is there a link in Alzheimer's disease?

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07588.X

CHIP-mediated stress recovery by sequential ubiquitination of substrates and Hsp70

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07588.X

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07588.X

Phosphorylation of arfaptin 2 at Ser260 by Akt Inhibits PolyQ-huntingtin-induced toxicity by rescuing proteasome impairment

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07588.X

Mitochondrial dysfunction in aging and Alzheimer's disease: strategies to protect neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07588.X

The role of the ubiquitin proteasome system in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07588.X

Reducing endogenous tau ameliorates amyloid beta-induced deficits in an Alzheimer's disease mouse model

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07588.X

Towards the treatment of polyglutamine diseases: the modulatory role of protein context

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07588.X

Parkin deletion causes cerebral and systemic amyloidosis in human mutated tau over-expressing mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07588.X

Parkin protects against mitochondrial toxins and beta-amyloid accumulation in skeletal muscle cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07588.X

Parkin reverses intracellular beta-amyloid accumulation and its negative effects on proteasome function.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07588.X

Chaperone functions of the E3 ubiquitin ligase CHIP.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07588.X

The novel cytosolic RING finger protein dactylidin is up-regulated in brains of patients with Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07588.X

In vivo evidence of CHIP up-regulation attenuating tau aggregation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07588.X

Molecular chaperone-mediated tau protein metabolism counteracts the formation of granular tau oligomers in human brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07588.X

Correlation between decrease in protein levels of ubiquitin ligase HRD1 and amyloid-beta production.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07588.X

Molecular chaperones as modulators of polyglutamine protein aggregation and toxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07588.X

Parkin binds the Rpn10 subunit of 26S proteasomes through its ubiquitin-like domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07588.X

Hsp90 regulates tau pathology through co-chaperone complexes in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07588.X

A synergistic dysfunction of mitochondrial fission/fusion dynamics and mitophagy in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07588.X

Parkin localizes to the Lewy bodies of Parkinson disease and dementia with Lewy bodies

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07588.X

Endoplasmic reticulum-localized amyloid beta-peptide is degraded in the cytosol by two distinct degradation pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07588.X

Activity-dependent ubiquitination of GluA1 mediates a distinct AMPA receptor endocytosis and sorting pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07588.X

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07588.X

Familial Parkinson disease gene product, parkin, is a ubiquitin-protein ligase

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07588.X

Ubiquitination of a new form of alpha-synuclein by parkin from human brain: implications for Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07588.X

CHIP-Hsc70 Complex Ubiquitinates Phosphorylated Tau and Enhances Cell Survival

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07588.X

The co-chaperone carboxyl terminus of Hsp70-interacting protein (CHIP) mediates alpha-synuclein degradation decisions between proteasomal and lysosomal pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07588.X

Regulation of PINK1-Parkin-mediated mitophagy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07588.X

BAG1 modulates huntingtin toxicity, aggregation, degradation, and subcellular distribution

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07588.X

Parkin is a component of an SCF-like ubiquitin ligase complex and protects postmitotic neurons from kainate excitotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07588.X

Rhes, a striatal specific protein, mediates mutant-huntingtin cytotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07588.X

Rhes, a physiologic regulator of sumoylation, enhances cross-sumoylation between the basic sumoylation enzymes E1 and Ubc9.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07588.X

Pael receptor, endoplasmic reticulum stress, and Parkinson?s disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07588.X

gamma-Secretase: successive tripeptide and tetrapeptide release from the transmembrane domain of beta-carboxyl terminal fragment.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07588.X

Dorfin prevents cell death by reducing mitochondrial localizing mutant superoxide dismutase 1 in a neuronal cell model of familial amyotrophic lateral sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07588.X

TRIM9, a novel brain-specific E3 ubiquitin ligase, is repressed in the brain of Parkinson's disease and dementia with Lewy bodies

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07588.X

CHIP targets toxic alpha-Synuclein oligomers for degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07588.X

Cellular turnover of the polyglutamine disease protein ataxin-3 is regulated by its catalytic activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07588.X

Parkin facilitates the elimination of expanded polyglutamine proteins and leads to preservation of proteasome function.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07588.X

S-nitrosylation of XIAP compromises neuronal survival in Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07588.X

E3 ligase STUB1/CHIP regulates NAD(P)H:quinone oxidoreductase 1 (NQO1) accumulation in aged brain, a process impaired in certain Alzheimer disease patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07588.X

Alzheimer disease with amygdala Lewy bodies: a distinct form of alpha-synucleinopathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07588.X

Can overexpression of parkin provide a novel strategy for neuroprotection in Parkinson's disease?

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07588.X

Parkin ubiquitinates and promotes the degradation of RanBP2

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07588.X

Parkin directly modulates 26S proteasome activity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07588.X

Intraneuronal amyloid β oligomers cause cell death via endoplasmic reticulum stress, endosomal/lysosomal leakage, and mitochondrial dysfunction in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07588.X

Differential regulation of proteasome activity in the nucleus and the synaptic terminals

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07588.X

CHIP promotes proteasomal degradation of familial ALS-linked mutant SOD1 by ubiquitinating Hsp/Hsc70.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07588.X

The familial Parkinson disease gene PARK2 is a multisite tumor suppressor on chromosome 6q25.2-27 that regulates cyclin E.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07588.X

PINK1-dependent recruitment of Parkin to mitochondria in mitophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07588.X

Tau reduction prevents Abeta-induced defects in axonal transport.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07588.X

TDP-43: an emerging new player in neurodegenerative diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07588.X

Impaired ubiquitin-proteasome system activity in the synapses of Huntington's disease mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07588.X

Parkin is not regulated by the unfolded protein response in human neuroblastoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07588.X

Increased glutathione S-transferase activity rescues dopaminergic neuron loss in a Drosophila model of Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07588.X

Posttranslational quality control: folding, refolding, and degrading proteins.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07588.X

In vivo suppression of polyglutamine neurotoxicity by C-terminus of Hsp70-interacting protein (CHIP) supports an aggregation model of pathogenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07588.X

The parkin protein as a therapeutic target in Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07588.X

Interactions between the quality control ubiquitin ligase CHIP and ubiquitin conjugating enzymes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07588.X

Parkin gene therapy for alpha-synucleinopathy: a rat model of Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07588.X

AtCHIP, a U-box-containing E3 ubiquitin ligase, plays a critical role in temperature stress tolerance in Arabidopsis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07588.X

Parkin suppresses dopaminergic neuron-selective neurotoxicity induced by Pael-R in Drosophila

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07588.X

Parkin stabilizes microtubules through strong binding mediated by three independent domains.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07588.X

Ubiquitin ligase Hrd1 enhances the degradation and suppresses the toxicity of polyglutamine-expanded huntingtin

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07588.X

Huntingtin interacts with the cue domain of gp78 and inhibits gp78 binding to ubiquitin and p97/VCP.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07588.X

Nitrosative stress linked to sporadic Parkinson's disease: S-nitrosylation of parkin regulates its E3 ubiquitin ligase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07588.X

Gp78, an ER associated E3, promotes SOD1 and ataxin-3 degradation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07588.X

Hsp90: a specialized but essential protein-folding tool

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07588.X

A foldable CFTR{Delta}F508 biogenic intermediate accumulates upon inhibition of the Hsc70-CHIP E3 ubiquitin ligase

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07588.X

Parkin is ubiquitinated by Nrdp1 and abrogates Nrdp1-induced oxidative stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07588.X

Parkin functions as an E2-dependent ubiquitin- protein ligase and promotes the degradation of the synaptic vesicle-associated protein, CDCrel-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07588.X

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07588.X

Carboxyl terminus of heat-shock cognate 70-interacting protein degrades tau regardless its phosphorylation status without affecting the spatial memory of the rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07588.X

Muscle atrophy and motor neuron degeneration in human NEDL1 transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07588.X

Structure of the Cul1-Rbx1-Skp1-F boxSkp2 SCF ubiquitin ligase complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07588.X

Molecular mechanisms and potential therapeutical targets in Huntington's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07588.X

Tumor necrosis factor receptor-associated factor 6 (TRAF6) associates with huntingtin protein and promotes its atypical ubiquitination to enhance aggregate formation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07588.X

The U box is a modified RING finger — a common domain in ubiquitination

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07588.X

Recognition of p63 by the E3 ligase ITCH: Effect of an ectodermal dysplasia mutant

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07588.X

A novel transactivation domain in parkin

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07588.X

Dangerous liaisons: polyglutamine meets HMGB

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07588.X

Prevention of β-Amyloid Neurotoxicity by Blockade of the Ubiquitin-Proteasome Proteolytic Pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07588.X

Erratum: Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07588.X